Honig P J, Charney E B
Am J Dis Child. 1982 Feb;136(2):121-4. doi: 10.1001/archpedi.1982.03970380033008.
We analyzed the history, physical examination findings, and skull roentgenograms of 72 children with headaches secondary to brain tumors to determine distinguishing features. Of 56 children, skull roentgenograms were abnormal in 54% (30). Abnormal findings from either the neurologic or ocular examination were present in 68 (94%) of these children at the time of brain tumor diagnosis. These abnormalities developed in 51 of 60 children (85%) within two months of the onset of their headaches. Clues for earlier diagnosis were frequently present in those patients whose conditions were diagnosed more than four months after the onset of their headaches. Recognition of those findings could have resulted in the diagnosis of brain tumor in 69 of 72 children (96%) within four months of the onset of headaches. During the first four months of headache complaints, children should be monitored closely.
我们分析了72例继发于脑肿瘤的头痛患儿的病史、体格检查结果和颅骨X线片,以确定其特征。56例患儿中,颅骨X线片异常者占54%(30例)。在脑肿瘤诊断时,这些患儿中有68例(94%)存在神经或眼科检查异常。这些异常在60例患儿中的51例(85%)于头痛发作后两个月内出现。在头痛发作四个月后才确诊的患儿中,早期诊断线索常常存在。识别这些表现可使72例患儿中的69例(96%)在头痛发作后四个月内诊断为脑肿瘤。在头痛主诉的前四个月,应对患儿进行密切监测。