Singh Lavan, Cariappa M P, Das N K
Senior Adviser (Pathology), Military Hospital Meerut, UP, India.
Associate Professor, Dept of Community Medicine, Armed Forces Medical College, Pune 411040, India.
Med J Armed Forces India. 2016 Dec;72(Suppl 1):S62-S66. doi: 10.1016/j.mjafi.2016.07.009. Epub 2016 Oct 17.
and other species are important pathogenic organisms and are responsible for various hospital infections. These are the predominant organisms found in pus and blood culture isolates. Infections arising due to these bacterial isolates are difficult to treat because of developing multidrug resistance.
Over a 1-year period at a tertiary care hospital laboratory, 524 Staphylococci species were isolated from pus, blood and urine samples and species-level identification was done.
formed the predominant species (70.8%) followed by coagulase-negative (CoNS) (29.20%). (91%) was the main isolate from pus samples; however, CoNS was isolated in equally higher proportion in blood culture (63.58%). Among the CoNS, was the main isolate (9.3%). β-Lactamase production, alteration of PBP and MLSB resistance were seen in variable degrees in different species.
CoNS group of Staphylococci is becoming an important cause of infection at tertiary care centres. The increased multidrug resistance among various species is a cause of great concern and requires adequate measures to prevent the spread of these microorganisms in the hospital and the community.
[具体细菌名称]及其他菌种是重要的致病生物,可引发各种医院感染。它们是在脓液和血培养分离物中发现的主要菌种。由于这些细菌分离株产生多重耐药性,由其引起的感染难以治疗。
在一家三级护理医院实验室的1年时间里,从脓液、血液和尿液样本中分离出524株葡萄球菌,并进行了菌种水平的鉴定。
[具体细菌名称]构成主要菌种(70.8%),其次是凝固酶阴性葡萄球菌(CoNS)(29.20%)。[具体细菌名称](91%)是脓液样本中的主要分离株;然而,在血培养中CoNS的分离比例同样较高(63.58%)。在CoNS中,[具体细菌名称]是主要分离株(9.3%)。不同菌种中可见不同程度的β-内酰胺酶产生、青霉素结合蛋白改变和大环内酯类-林可酰胺类-链阳菌素B耐药。
葡萄球菌的CoNS组正成为三级护理中心感染的重要原因。各种[具体细菌名称]菌种中多重耐药性增加令人高度担忧,需要采取适当措施防止这些微生物在医院和社区传播。