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本文引用的文献

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Inducible Clindamycin Resistance in Staphylococcus aureus Isolated from Clinical Samples.从临床样本中分离出的金黄色葡萄球菌中的诱导型克林霉素耐药性。
J Lab Physicians. 2011 Jan;3(1):25-7. doi: 10.4103/0974-2727.78558.
2
Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic.社区相关性耐甲氧西林金黄色葡萄球菌:一种新兴流行疾病的流行病学和临床后果。
Clin Microbiol Rev. 2010 Jul;23(3):616-87. doi: 10.1128/CMR.00081-09.
3
Epidemiology of methicillin-resistant Staphylococcus aureus.耐甲氧西林金黄色葡萄球菌的流行病学
Clin Infect Dis. 2008 Jun 1;46 Suppl 5:S344-9. doi: 10.1086/533590.
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Invasive methicillin-resistant Staphylococcus aureus infections in the United States.美国侵袭性耐甲氧西林金黄色葡萄球菌感染
JAMA. 2007 Oct 17;298(15):1763-71. doi: 10.1001/jama.298.15.1763.
5
Species distribution and antibiotic sensitivity pattern of Coagulase negative staphylococci isolated from various clinical specimens.从各种临床标本中分离出的凝固酶阴性葡萄球菌的菌种分布及抗生素敏感性模式。
Indian J Med Microbiol. 2002 Jan-Mar;20(1):45-6.
6
Species distribution & antimicrobial susceptibility of coagulase negative Staphylococci in a tertiary care hospital.一家三级医院中凝固酶阴性葡萄球菌的菌种分布及抗菌药敏情况
Indian J Med Res. 2006 Apr;123(4):569-70.
7
Practical disk diffusion method for detection of inducible clindamycin resistance in Staphylococcus aureus and coagulase-negative staphylococci.检测金黄色葡萄球菌和凝固酶阴性葡萄球菌中诱导性克林霉素耐药性的实用纸片扩散法。
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一家三级护理医院分离出的各种物种的药敏模式。

Drug sensitivity pattern of various species isolated at a tertiary care hospital.

作者信息

Singh Lavan, Cariappa M P, Das N K

机构信息

Senior Adviser (Pathology), Military Hospital Meerut, UP, India.

Associate Professor, Dept of Community Medicine, Armed Forces Medical College, Pune 411040, India.

出版信息

Med J Armed Forces India. 2016 Dec;72(Suppl 1):S62-S66. doi: 10.1016/j.mjafi.2016.07.009. Epub 2016 Oct 17.

DOI:10.1016/j.mjafi.2016.07.009
PMID:28050073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5192222/
Abstract

BACKGROUND

and other species are important pathogenic organisms and are responsible for various hospital infections. These are the predominant organisms found in pus and blood culture isolates. Infections arising due to these bacterial isolates are difficult to treat because of developing multidrug resistance.

METHODS

Over a 1-year period at a tertiary care hospital laboratory, 524 Staphylococci species were isolated from pus, blood and urine samples and species-level identification was done.

RESULTS

formed the predominant species (70.8%) followed by coagulase-negative (CoNS) (29.20%). (91%) was the main isolate from pus samples; however, CoNS was isolated in equally higher proportion in blood culture (63.58%). Among the CoNS, was the main isolate (9.3%). β-Lactamase production, alteration of PBP and MLSB resistance were seen in variable degrees in different species.

CONCLUSION

CoNS group of Staphylococci is becoming an important cause of infection at tertiary care centres. The increased multidrug resistance among various species is a cause of great concern and requires adequate measures to prevent the spread of these microorganisms in the hospital and the community.

摘要

背景

[具体细菌名称]及其他菌种是重要的致病生物,可引发各种医院感染。它们是在脓液和血培养分离物中发现的主要菌种。由于这些细菌分离株产生多重耐药性,由其引起的感染难以治疗。

方法

在一家三级护理医院实验室的1年时间里,从脓液、血液和尿液样本中分离出524株葡萄球菌,并进行了菌种水平的鉴定。

结果

[具体细菌名称]构成主要菌种(70.8%),其次是凝固酶阴性葡萄球菌(CoNS)(29.20%)。[具体细菌名称](91%)是脓液样本中的主要分离株;然而,在血培养中CoNS的分离比例同样较高(63.58%)。在CoNS中,[具体细菌名称]是主要分离株(9.3%)。不同菌种中可见不同程度的β-内酰胺酶产生、青霉素结合蛋白改变和大环内酯类-林可酰胺类-链阳菌素B耐药。

结论

葡萄球菌的CoNS组正成为三级护理中心感染的重要原因。各种[具体细菌名称]菌种中多重耐药性增加令人高度担忧,需要采取适当措施防止这些微生物在医院和社区传播。