Gunawat Prashant, Shaikh Salman Tehran, Karmarkar Vikram, Deopujari Chandrashekhar
Consultant Neurosurgeon, Department of Neurosurgery, Bombay Hospital Institute of Medical Sciences , Mumbai, Maharashtra, India .
Senior Resident, Department of Neurosurgery, Bombay Hospital Institute of Medical Sciences , Mumbai, Maharashtra, India .
J Clin Diagn Res. 2016 Nov;10(11):PD15-PD16. doi: 10.7860/JCDR/2016/22705.8836. Epub 2016 Nov 1.
Onyx is a liquid embolic agent presently gaining wide acceptance for embolisation of multiple vascular cranial pathologies like Arteriovenous Malformation (AVM) and Arteriovenous Fistula (AVF). Onyx stays in the nidus of vascular pathology and initiates inflammatory response leading to thrombosis and subsequently resulting in occlusion of vascular nidus. However, if onyx spills into the surrounding brain tissue, reaction occurs in the form of foreign body inflammatory reaction. This is one of the very few cases in literature whereby embolisation of AVM with onyx lead to granuloma formation which needed surgical excision. It presented with limb weakness and seizure episodes.
奥尼克斯是一种液体栓塞剂，目前在多种颅内血管病变如动静脉畸形（AVM）和动静脉瘘（AVF）的栓塞治疗中得到广泛应用。奥尼克斯停留在血管病变的病灶内，引发炎症反应导致血栓形成，随后致使血管病灶闭塞。然而，如果奥尼克斯溢入周围脑组织，会以异物炎症反应的形式发生反应。这是文献中极少数用奥尼克斯栓塞AVM导致肉芽肿形成并需要手术切除的病例之一。该病例表现为肢体无力和癫痫发作。
