Mosallanejad Asieh, Tabatabai Shahrzad, Shakiba Marjan, Alaei Mohammad Reza, Saneifard Hedieh
Assistant Professor, Imam Hosein Medical Center, Shahid Beheshti University of Medical Sciencce , Tehran, Iran .
Assistant Professor, Mofid Children Hospital, Shahid Beheshti University of Medical Sciencce , Tehran, Iran .
J Clin Diagn Res. 2016 Nov;10(11):SD07-SD08. doi: 10.7860/JCDR/2016/21562.8880. Epub 2016 Nov 1.
Ovarian hyperstimulation syndrome is a rare disease among preterm infants. This syndrome was first described in 1985 in four infants with a gestational age of <30 weeks. Several explanations for this syndrome have been suggested namely the immaturity of Hypothalamic-Pituitary-Gonadal (HPG) axis, lack of negative feedback, increased sensitivity of Follicle Stimulating Hormone (FSH) receptors due to mutation and high level of estradiol. In this report, a case of hyperstimulation syndrome in a newborn with gestational age of 30 weeks is presented and the probable mechanisms in the literature are discussed.
卵巢过度刺激综合征在早产儿中是一种罕见疾病。该综合征于1985年首次在4例孕周小于30周的婴儿中被描述。针对该综合征提出了几种解释，即下丘脑 - 垂体 - 性腺（HPG）轴不成熟、缺乏负反馈、由于突变导致促卵泡生成素（FSH）受体敏感性增加以及雌二醇水平升高。在本报告中，呈现了1例孕周为30周的新生儿发生过度刺激综合征的病例，并讨论了文献中的可能机制。
