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[卷烟制造工人血清总IgE及特异性抗螨IgE抗体测定的初步研究]

[A preliminary study on determining total serum IgE and specific anti-mite IgE antibody in cigarette manufacturing workers].

作者信息

Chen H Y

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 1989 Jun;12(3):153-4, 191.

PMID:2805145
Abstract

Total serum IgE and specific anti-mite IgE antibody (IgEAM) were determined in cigarette manufacturing workers with (but not asthma) or without respiratory symptoms (30 cases in each) 16 patients with bronchial asthma, 8 with asthmatic bronchitis and 6 with other respiratory diseases. The total serum IgE level was significantly higher in symptomatic workers (825.8 +/- 22.3 IU/ml) than that of asymptomatic (162.1 +/- 28.0 IU/ml) (P less than 0.001) and patients with other respiratory diseases (P less than 0.05), but was lower than that of patients with bronchial asthma (3310.3 +/- 26.3 IU/ml) and asthmatic bronchitis (2278.4 +/- 25.5 IU/ml) (P less than 0.001). IgEAM was undetectable in all cases except one with asymptomatic worker and one with asthma. The respiratory symptoms in these workers seemed to be related to type I allergic reaction, possibly due to the chemical components in the cigarettes.

摘要

对有(但非哮喘)或无呼吸道症状的香烟制造工人(各30例)、16例支气管哮喘患者、8例喘息性支气管炎患者和6例其他呼吸道疾病患者测定了血清总IgE和特异性抗螨IgE抗体(IgEAM)。有症状工人的血清总IgE水平(825.8±22.3 IU/ml)显著高于无症状工人(162.1±28.0 IU/ml)(P<0.001)和其他呼吸道疾病患者(P<0.05),但低于支气管哮喘患者(3310.3±26.3 IU/ml)和喘息性支气管炎患者(2278.4±25.5 IU/ml)(P<0.001)。除1例无症状工人和1例哮喘患者外,所有病例均未检测到IgEAM。这些工人的呼吸道症状似乎与I型过敏反应有关,可能是由于香烟中的化学成分所致。

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