Staessen Jan A, Li Yan, Hara Azusa, Asayama Kei, Dolan Eamon, O'Brien Eoin
Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
R&D Group VitaK, Maastricht University, Maastricht, The Netherlands.
Am J Hypertens. 2017 May 1;30(5):453-463. doi: 10.1093/ajh/hpw148.
The rational management of hypertension (HT) inevitably starts with accurate measurement of blood pressure (BP). The recently published Systolic Blood Pressure Intervention Trial implemented automated office BP measurement. However, event-driven studies have overwhelmingly indicated that out-of-the-office BP monitoring is a prerequisite for risk stratification and for identifying the need of initiating or adjusting antihypertensive drug treatment. 24-Hour ambulatory BP monitoring is the preferred method of BP measurement and addresses major issues not covered by conventional or automated office BP measurement or home BP monitoring, such as reliably diagnosing nocturnal HT (the time window of the day during which BP is most predictive of adverse cardiovascular outcome), hypotension, or masked HT, a condition that affects 15% of the general populations and carries a risk equal to that of HT on both office and out-of-the-office BP measurement. Moreover, 24-hour ambulatory BP monitoring is cost-effective. Outcome-driven criteria support single BP thresholds that can be applied in both sexes and across the age range. In conclusion, the overall evidence now overwhelmingly shows that ambulatory BP monitoring is mandatory for the proper management of HT. Health care providers should therefore facilitate access to this technique in both primary and specialized care.
高血压(HT)的合理管理必然始于血压(BP)的准确测量。最近发表的收缩压干预试验采用了自动诊室血压测量。然而,大量事件驱动研究表明,诊室外血压监测是风险分层以及确定启动或调整抗高血压药物治疗需求的先决条件。24小时动态血压监测是首选的血压测量方法,可解决传统或自动诊室血压测量或家庭血压监测未涵盖的主要问题,如可靠诊断夜间高血压(一天中血压最能预测不良心血管结局的时间段)、低血压或隐匿性高血压,隐匿性高血压影响15%的普通人群,其在诊室和诊室外血压测量中的风险与高血压相当。此外,24小时动态血压监测具有成本效益。基于结果的标准支持可应用于男女及各年龄段的单一血压阈值。总之,目前的总体证据压倒性地表明,动态血压监测对于高血压的恰当管理是必不可少的。因此,医疗保健提供者应在初级和专科护理中都促进使用这项技术。