Ahmad Irfan, Chufal Kundan Singh, Bhargava Amit, Bashir Irfan
Department of Radiation Oncology, Batra Hospital & Medical Research Centre, New Delhi, Delhi, India.
Department of Medical Oncology, Batra Hospital & Medical Research Centre, New Delhi, Delhi, India.
BMJ Case Rep. 2017 Jan 4;2017:bcr2016217461. doi: 10.1136/bcr-2016-217461.
A 48-year-old woman presented with symptoms of lower abdominal pain and vaginal discharge for 6 months. Clinical examination and pelvic ultrasound scan suggested a diagnosis of infected Gartner's cyst, for which she underwent vaginal cystectomy. However, histopathology and immunohistochemistry revealed a diagnosis of primitive neuroectodermal tumour of the cervix. Further investigations revealed the stage to be FIGO IIIB, which was inoperable. She received neoadjuvant chemotherapy (vincristine, adriamycin, cyclophosphamide alternating with ifosfamide, cisplatin and etoposide, every 21 days), but the tumour did not respond to treatment and she was started on radiotherapy with definitive intent (55.8 Gray in 31 fractions over 6.2 weeks). A PET-CT performed 2 months after completion of radiotherapy showed complete response, and she is now receiving adjuvant chemotherapy.
一名48岁女性出现下腹痛和阴道分泌物症状6个月。临床检查和盆腔超声扫描提示诊断为感染性加特纳囊肿，她因此接受了阴道囊肿切除术。然而，组织病理学和免疫组化显示诊断为宫颈原始神经外胚层肿瘤。进一步检查显示分期为国际妇产科联盟（FIGO）IIIB期，无法手术。她接受了新辅助化疗（长春新碱、阿霉素、环磷酰胺与异环磷酰胺、顺铂和依托泊苷交替使用，每21天一次），但肿瘤对治疗无反应，随后开始进行根治性放疗（6.2周内31次分割，共55.8格雷）。放疗结束2个月后进行的PET-CT显示完全缓解，她目前正在接受辅助化疗。
