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中国自闭症谱系障碍学龄前儿童母亲中孕产妇情感障碍的患病率。

Prevalence of Maternal Affective Disorders in Chinese Mothers of Preschool Children with Autism Spectrum Disorders.

作者信息

Yu Y W, Chung K H, Lee Y K, Lam W C, Yiu M Gc

机构信息

Department of Psychiatry, Kwai Chung Hospital, Hong Kong SAR, China.

Department of Psychiatry, United Christian Hospital, Hong Kong SAR, China.

出版信息

East Asian Arch Psychiatry. 2016 Dec;26(4):121-8.

Abstract

OBJECTIVES

To evaluate the prevalence of affective disorders and identify their associated factors among Chinese mothers of preschool children diagnosed with autism spectrum disorders.

METHODS

This cross-sectional study was conducted at the Autism Spectrum Disorders Multidisciplinary Clinic of the United Christian Hospital from August 2012 to June 2013. All mothers of a consecutive series of preschool children diagnosed with autism spectrum disorders at their first visit to the clinic were recruited. Information regarding the child-related, maternal, and environmental factors was collected. Psychiatric diagnoses were made according to the Chinese-Bilingual Structured Clinical Interview for DSM-IV Axis I Disorders. Independent factors associated with maternal affective disorders were determined by univariate and multivariate analyses.

RESULTS

Of the 121 subjects, the point prevalence of affective disorders as a group was 29.8%. The point prevalence of major depressive disorders, adjustment disorders, anxiety disorders, and bipolar affective disorders was 14.9%, 10.7%, 3.3% and 0.8%, respectively. A higher level of disruptive and self-absorbed behaviours in the children (as assessed by the Developmental Behaviour Checklist), a higher level of affiliate stigma (as assessed by 22-item Affiliate Stigma Scale), and a history of psychiatric disorders were independently associated with current affective disorders.

CONCLUSION

Psychiatric disorders, predominantly affective disorders, are common among Chinese mothers of preschool children with autism spectrum disorders. Identification of independent factors associated with maternal affective disorders can aid in the early detection of cases and planning of early intervention programmes to address both child and maternal psychological needs.

摘要

目的

评估情感障碍的患病率,并确定中国学龄前自闭症谱系障碍患儿母亲中情感障碍的相关因素。

方法

本横断面研究于2012年8月至2013年6月在联合医院自闭症谱系障碍多学科诊所进行。招募了所有首次到诊所就诊且被诊断为自闭症谱系障碍的学龄前儿童的母亲。收集了与儿童、母亲和环境因素相关的信息。根据《DSM-IV轴I障碍的中文-双语结构化临床访谈》进行精神科诊断。通过单因素和多因素分析确定与母亲情感障碍相关的独立因素。

结果

在121名受试者中,情感障碍作为一组的时点患病率为29.8%。重度抑郁症、适应障碍、焦虑症和双相情感障碍的时点患病率分别为14.9%、10.7%、3.3%和0.8%。儿童中更高水平的破坏性行为和自我专注行为(通过《发育行为检查表》评估)、更高水平的关联污名(通过22项关联污名量表评估)以及精神疾病史与当前情感障碍独立相关。

结论

精神疾病,主要是情感障碍,在患有自闭症谱系障碍的中国学龄前儿童母亲中很常见。识别与母亲情感障碍相关的独立因素有助于早期发现病例,并规划早期干预项目以满足儿童和母亲的心理需求。

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