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肾上腺碰撞瘤:色素性肾上腺皮质嗜酸性细胞瘤与神经节神经瘤并存

Adrenal Collision Tumor: Coexistence of Pigmented Adrenal Cortical Oncocytoma and Ganglioneuroma.

作者信息

Lee Hye Seung, Choi Yoo Jin, Kim Chungyeul, Kim Baek-Hui

机构信息

Department of Pathology, Korea University School of Medicine, Seoul, Republic of Korea.

出版信息

Case Rep Surg. 2016;2016:5790645. doi: 10.1155/2016/5790645. Epub 2016 Dec 8.

Abstract

. Adrenal collision tumors (ACTs), in which distinct tumors coexist without intermingling in the same adrenal gland, are rare and their actual prevalence is unknown. ACTs commonly consist of adrenal cortical adenoma, pheochromocytoma, or metastatic malignant tumor. . A 32-year-old woman who had been experiencing gastric discomfort for one month was referred to our hospital with abnormal imaging findings. The physical examination and the laboratory data including endocrine studies were unremarkable. Abdomen computed tomography (CT) and magnetic resonance imaging (MRI) showed two adjacent masses in the left suprarenal fossa, and a laparoscopic left adrenalectomy was done. Histological and immunohistochemical (IHC) examinations revealed two distinct tumors: a pigmented adrenal cortical oncocytoma (ACO) and a ganglioneuroma, respectively. . Both tumors are rare in the adrenal gland and exist as ACTs only exceptionally rarely. This is the first reported case of coexisting oncocytoma and ganglioneuroma in the same adrenal gland to our knowledge.

摘要

肾上腺碰撞瘤(ACTs)是指不同的肿瘤在同一肾上腺内共存但不相互混杂,这种肿瘤较为罕见,其实际发病率尚不清楚。ACTs通常由肾上腺皮质腺瘤、嗜铬细胞瘤或转移性恶性肿瘤组成。一名32岁女性因胃部不适1个月前来我院就诊,影像学检查发现异常。体格检查及包括内分泌检查在内的实验室检查均无异常。腹部计算机断层扫描(CT)和磁共振成像(MRI)显示左肾上腺窝有两个相邻肿块,遂行腹腔镜左肾上腺切除术。组织学和免疫组化(IHC)检查显示为两种不同的肿瘤,分别为色素性肾上腺皮质嗜酸细胞瘤(ACO)和神经节神经瘤。这两种肿瘤在肾上腺中都很罕见,仅极个别情况下以ACTs形式存在。据我们所知,这是首例同一肾上腺内共存嗜酸细胞瘤和神经节神经瘤的病例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e4f/5178330/721f2b587b20/CRIS2016-5790645.001.jpg

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