Bentsen Mariann H L, Eriksen Morten, Olsen Merete S, Markestad Trond, Halvorsen Thomas
Dept of Pediatrics, Haukeland University Hospital, Bergen, Norway; Dept of Clinical Science, Faculty of Medicine and Odontology, University of Bergen, Bergen, Norway.
VoluSense AS, Bergen, Norway.
ERJ Open Res. 2016 Nov 24;2(4). doi: 10.1183/23120541.00062-2016. eCollection 2016 Oct.
Reliable, accurate and noninvasive methods for measuring lung function in infants are desirable. Electromagnetic inductance plethysmography has been used to perform infant spirometry and VoluSense Pediatrics (VSP) (VoluSense, Bergen, Norway) represents an updated version of this technique. We aimed to examine its accuracy compared to a validated system measuring airflow a facemask using an ultrasonic flowmeter. We tested 30 infants with postmenstrual ages between 36 to 43 weeks and weights from 2.3 to 4.8 kg, applying both methods simultaneously and applying VSP alone. Agreement between the methods was calculated using Bland-Altman analyses and we also estimated the effect of applying the mask. Mean differences for all breathing parameters were within ±5.5% and limits of agreement between the two methods were acceptable, except perhaps for peak tidal expiratory flow (PTEF). Application of the facemask significantly increased tidal volume, minute ventilation, PTEF, the ratio of inspiratory to expiratory time and the ratio of expiratory flow at 50% of expired volume to PTEF. VSP accurately measured tidal breathing parameters and seems well suited for tidal breathing measurements in infants under treatment with equipment that precludes the use of a facemask.
需要可靠、准确且无创的方法来测量婴儿的肺功能。电磁感应体积描记法已用于进行婴儿肺量计测定,而VoluSense Pediatrics(VSP,挪威卑尔根的VoluSense公司)代表了该技术的升级版。我们旨在将其与使用超声流量计的面罩这一经过验证的气流测量系统相比较,检验其准确性。我们测试了30名孕龄在36至43周之间、体重在2.3至4.8千克之间的婴儿,同时应用这两种方法并单独应用VSP。使用Bland-Altman分析计算两种方法之间的一致性,我们还估计了使用面罩的影响。除了可能的呼气潮气量峰值(PTEF)外,所有呼吸参数的平均差异在±5.5%以内,两种方法之间的一致性界限是可接受的。使用面罩显著增加了潮气量、分钟通气量、PTEF、吸气与呼气时间之比以及呼出体积50%时的呼气流量与PTEF之比。VSP准确地测量了潮气呼吸参数,似乎非常适合在使用无法使用面罩的设备进行治疗的婴儿中进行潮气呼吸测量。