Esposito Marcello, Peluso Silvio, Dubbioso Raffaele, Allocca Roberto, Iorillo Filippo, Coppola Antonietta, Santoro Lucio
Department of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, Via Pansini 5, 80131, Naples, Italy.
Neurol Sci. 2017 Apr;38(4):683-686. doi: 10.1007/s10072-016-2799-z. Epub 2017 Jan 4.
Aim of this study is to identify factors contributing the occurrence of neck lateral shift (LS) in patients with cervical dystonia (CD). A retrospective analysis focused on the treatment with botulinum toxin (BTX) was conducted on 38 consecutive idiopathic CD patients comparing subjects with and without LS. The main result was the evidence of a significantly higher BTX inter-side dose difference in patients with LS suggesting that this uncommon phenotype may be an artifact of chronic therapy with BTX.
本研究的目的是确定导致颈部肌张力障碍(CD)患者出现颈部侧移(LS)的因素。对38例连续性特发性CD患者进行了一项侧重于肉毒毒素(BTX)治疗的回顾性分析,比较有和没有LS的受试者。主要结果是有LS的患者中BTX侧间剂量差异显著更高,这表明这种不常见的表型可能是BTX长期治疗的一种假象。