通过 NaBrO 对 NaSOCF 的单电子氧化实现烯烃的自由基溴三氟甲基化。
Free-Radical Bromotrifluoromethylation of Olefin via Single-Electron Oxidation of NaSOCF by NaBrO.
机构信息
School of Petrochemical Engineering, Institute for Natural and Synthetic Organic Chemistry, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University , Changzhou 213164, P. R. China.
State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, Gansu 730000, P. R. China.
出版信息
J Org Chem. 2017 Feb 3;82(3):1649-1656. doi: 10.1021/acs.joc.6b02812. Epub 2017 Jan 17.
A free-radical bromotrifluoromethylation of olefin by using NaSOCF and NaBrO has been achieved. Sodium bromate acts not only as a single-electron oxidant but also as a bromine source. A radical-clock experiment and electron-spin-resonance detection support a radical process.
通过使用 NaSOCF 和 NaBrO，实现了烯烃的自由基溴三氟甲基化。溴酸钠不仅充当单电子氧化剂，还充当溴源。自由基钟实验和电子自旋共振检测支持自由基过程。
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