Arnold Arthur P
Department of Psychology and Brain Research Institute, University of California, Los Angeles, California 90024.
J Histochem Cytochem. 1981 Jan;29(1A_suppl):207-211. doi: 10.1177/29.1A_SUPPL.7288157.
Two types of quantitative criteria are compared that have been used to discriminate labeled and nonlabeled cells in steroid autoradiograms: multiplicative criteria and a criterion based on the Poisson distribution. Several factors affect the accuracy of the assessment of cell labeling, including variations in the length of exposure, variations in cell size, and possible nonlinearities in the grain density of autoradiograms as a function of exposure time. These factors have a greater effect on the accuracy of the determination of cell labeling when using multiplicative criteria, so that the Poisson criterion is more suitable.
乘法标准和基于泊松分布的标准。有几个因素会影响细胞标记评估的准确性，包括曝光时间长度的变化、细胞大小的变化以及放射自显影片的颗粒密度随曝光时间可能存在的非线性。在使用乘法标准时，这些因素对细胞标记测定准确性的影响更大，因此泊松标准更合适。
