Çelebi Sözener Zeynep, Aydın Ömür, Demirel Yavuz Selim, Soyyiğit Şadan, Çerçi Pamir, Kendirlinan Reşat, Bavbek Sevim, Çelik Gülfem Elif, Misirligil Zeynep, Sin Betül Ayşe, Keleşoğlu Arif, Mungan Dilşad
a Department of Chest Diseases, Division of Allergy and Clinical Immunology , Ankara University School of Medicine , Ankara , Turkey.
b Ankara Dışkapı Yıldırım Beyazıt Training and Research Hospital , Ankara , Turkey.
J Asthma. 2017 Nov;54(9):930-937. doi: 10.1080/02770903.2016.1277541. Epub 2017 Jan 5.
The incidence of occupational asthma (OA) is increasing worldwide. In this study, we first aimed to document the rate of diagnosis of OA among patients who were referred to our clinic from the Social Security Institution and the factors that affected diagnosis; secondly, we aimed to assess the consistency of the medical and legal diagnoses.
The study involved 132 consecutive patients who were referred to our clinic for the evaluation of OA between 2010 and 2015. Detailed workplace history, the tools used in the diagnosis such as peak expiratory flow (PEF) monitoring and bronchial provocation tests, and the final medical diagnosis were recorded from case files.
Asthma was diagnosed in 75% (n = 99) of the patients. Among them, 22.2% were diagnosed as having OA. The diagnosis was confirmed by serial PEF measurements, non-specific bronchial hyperreactivity assessment or both of the tests both at work and off-work periods. OA diagnosis was mostly established in active workers (72.7%). The legal diagnosis period was completed in 54.5% of these 22 patients, and 50% (n = 11) were officially diagnosed as having OA with a 91.6% concordance with medical diagnosis.
This study verifies the importance of diagnosing asthma correctly as a first step in the evaluation of OA. Diagnostic tests other than specific provocation tests could be preferential in patients who still work in the same field. We believe that cooperation with the patient's occupational physician and adequate recognition of the work environment will improve the consistency of legal and medical diagnoses.
职业性哮喘(OA)在全球范围内的发病率正在上升。在本研究中,我们首先旨在记录从社会保障机构转介至我们诊所的患者中OA的诊断率以及影响诊断的因素;其次,我们旨在评估医学诊断与法律诊断的一致性。
该研究纳入了2010年至2015年间连续转介至我们诊所评估OA的132例患者。从病例档案中记录详细的工作场所病史、诊断中使用的工具,如呼气峰值流量(PEF)监测和支气管激发试验,以及最终的医学诊断。
75%(n = 99)的患者被诊断为哮喘。其中,22.2%被诊断为患有OA。通过在工作期间和非工作期间进行连续PEF测量、非特异性支气管高反应性评估或两项测试来确诊。OA诊断大多在在职员工中确立(72.7%)。这22例患者中有54.5%完成了法律诊断期,50%(n = 11)被正式诊断为患有OA,与医学诊断的一致性为91.6%。
本研究证实了正确诊断哮喘作为OA评估第一步的重要性。对于仍在同一领域工作的患者,除特异性激发试验外的诊断测试可能更具优势。我们认为与患者的职业医生合作以及充分了解工作环境将提高法律诊断与医学诊断的一致性。