Yarcı Gursoy Aslı, Caglar Gamze S, Demirtas Selda
Ufuk University Faculty of Medicine, Obstetrics and Gynecology Department, Ankara, Turkey.
Ufuk University Faculty of Medicine, Obstetrics and Gynecology Department, Ankara, Turkey.
Eur J Obstet Gynecol Reprod Biol. 2017 Mar;210:182-188. doi: 10.1016/j.ejogrb.2016.12.022. Epub 2016 Dec 23.
Ischemia modified albumin is a novel marker of ischemia generated due to hypooxygenation and increased hydroxyl free radicals in low pH. The molecule has been licenced for clinical use as an early marker for acute coronary syndrome in cardiology. Since presence of ischemia might have serious and sometimes devastating effects in perinatology, various researches have evaluated its value in different clinical conditions. This narrative review aims to summarize the literature concerning the value of IMA in perinatology and guide for further research.
缺血修饰白蛋白是一种因低氧血症和低pH值下羟自由基增加而产生的新型缺血标志物。该分子已被批准用于临床,作为心脏病学中急性冠状动脉综合征的早期标志物。由于缺血的存在可能在围产医学中产生严重且有时是毁灭性的影响,因此各种研究评估了其在不同临床情况下的价值。本叙述性综述旨在总结有关缺血修饰白蛋白在围产医学中价值的文献,并为进一步研究提供指导。