日本一家医院卡他莫拉菌临床分离株对β-内酰胺类抗生素的药敏性及BROβ-内酰胺酶的产生情况
Antimicrobial susceptibility to β-lactam antibiotics and production of BRO β-lactamase in clinical isolates of Moraxella catarrhalis from a Japanese hospital.
作者信息
Yamada Kageto, Arai Katsumi, Saito Ryoichi
机构信息
Department of Clinical Laboratory, Tokyo Metropolitan Health and Medical Treatment Corporation Toshima Hospital, Tokyo, Japan; Department of Biomolecular Science, Faculty of Science, Toho University, Chiba, Japan.
Department of Clinical Laboratory, Tokyo Metropolitan Health and Medical Treatment Corporation Toshima Hospital, Tokyo, Japan.
出版信息
J Microbiol Immunol Infect. 2017 Jun;50(3):386-389. doi: 10.1016/j.jmii.2016.08.003. Epub 2016 Dec 18.
We investigated BRO-β-lactamase production of Moraxella catarrhalis isolates and its antimicrobial susceptibility to β-lactams. Of the 233 isolates, 232 were BRO producers and 224 were BRO-1 producers. Four isolates exhibited elevated ceftriaxone minimum inhibitory concentration (2 μg/mL) and different pulsed-field gel electrophoresis patterns and we expect this number to increase in the near future.
我们研究了卡他莫拉菌分离株的BRO-β-内酰胺酶产生情况及其对β-内酰胺类药物的抗菌敏感性。在233株分离株中，232株产生BRO，224株产生BRO-1。4株分离株的头孢曲松最低抑菌浓度升高（2μg/mL），且脉冲场凝胶电泳图谱不同，我们预计在不久的将来这一数字会增加。
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