Ortiz-Toquero Sara, Rodriguez Guadalupe, de Juan Victoria, Martin Raul
Universidad de Valladolid, Departamento de Física Teórica, Atómica y Óptica, Paseo de Belén, 7 - Campus Miguel Delibes, 47011 Valladolid, Spain; Universidad de Valladolid, Instituto Universitario de Oftalmobiología Aplicada (IOBA), Paseo de Belén, 17 - Campus Miguel Delibes, 47011 Valladolid, Spain; Optometry Research Group, IOBA Eye Institute, School of Optometry, University of Valladolid, Valladolid, Spain.
Universidad de Valladolid, Instituto Universitario de Oftalmobiología Aplicada (IOBA), Paseo de Belén, 17 - Campus Miguel Delibes, 47011 Valladolid, Spain; Optometry Research Group, IOBA Eye Institute, School of Optometry, University of Valladolid, Valladolid, Spain; Department of Ophthalmology, Ramón y Cajal University Hospital, Madrid, Spain.
Cont Lens Anterior Eye. 2017 Jun;40(3):143-150. doi: 10.1016/j.clae.2016.12.009. Epub 2017 Jan 2.
To calculate and validate a new web-based algorithm for selecting the back optic zone radius (BOZR) of spherical gas permeable (GP) lens in keratoconus eyes.
A retrospective calculation (n=35; multiple regression analysis) and a posterior prospective validation (new sample of 50 keratoconus eyes) of a new algorithm to select the BOZR of spherical KAKC design GP lenses (Conoptica) in keratoconus were conducted. BOZR calculated with the new algorithm, manufacturer guidelines and APEX software were compared with the BOZR that was finally prescribed. Number of diagnostic lenses, ordered lenses and visits to achieve optimal fitting were recorded and compared those obtained for a control group [50 healthy eyes fitted with spherical GP (BIAS design; Conoptica)].
The new algorithm highly correlated with the final BOZR fitted (r=0.825, p<0.001). BOZR of the first diagnostic lens using the new algorithm demonstrated lower difference with the final BOZR prescribed (-0.01±0.12mm, p=0.65; 58% difference≤0.05mm) than with the manufacturer guidelines (+0.12±0.22mm, p<0.001; 26% difference≤0.05mm) and APEX software (-0.14±0.16mm, p=0.001; 34% difference≤0.05mm). Close numbers of diagnostic lens (1.6±0.8, 1.3±0.5; p=0.02), ordered lens (1.4±0.6, 1.1±0.3; P<0.001), and visits (3.4±0.7, 3.2±0.4; p=0.08) were required to fit keratoconus and healthy eyes, respectively.
This new algorithm (free access at www.calculens.com) improves spherical KAKC GP fitting in keratoconus and can reduce the practitioner and patient chair time to achieve a final acceptable fit in keratoconus. This algorithm reduces differences between keratoconus GP fitting (KAKC design) and standard GP (BIAS design) lenses fitting in healthy eyes.
计算并验证一种新的基于网络的算法，用于选择圆锥角膜眼的球面透气性（GP）镜片的后光学区半径（BOZR）。
对一种用于选择圆锥角膜中球面KAKC设计GP镜片（Conoptica）的BOZR的新算法进行回顾性计算（n = 35；多元回归分析）和事后前瞻性验证（50只圆锥角膜眼的新样本）。将用新算法、制造商指南和APEX软件计算出的BOZR与最终处方的BOZR进行比较。记录达到最佳适配所需的诊断镜片数量、订购镜片数量和就诊次数，并与对照组[50只佩戴球面GP（BIAS设计；Conoptica）的健康眼睛]的相应数据进行比较。
新算法与最终适配的BOZR高度相关（r = 0.825，p < 0.001）。使用新算法的第一个诊断镜片的BOZR与最终处方的BOZR之间的差异（-0.01±0.12mm，p = 0.65；58%的差异≤0.05mm）小于与制造商指南（+0.12±0.22mm，p < 0.001；26%的差异≤0.05mm）和APEX软件（-0.14±0.16mm，p = 0.001；34%的差异≤0.05mm）之间的差异。适配圆锥角膜眼和健康眼睛分别需要的诊断镜片数量（1.6±0.8，1.3±0.5；p = 0.02）、订购镜片数量（1.4±0.6，1.1±0.3；P < 0.001）和就诊次数（3.4±0.7，3.2±0.4；p = 0.08）相近。
这种新算法（可在www.calculens.com免费获取）改善了圆锥角膜中球面KAKC GP的适配情况，并可减少从业者和患者的就诊时间，以在圆锥角膜中实现最终可接受的适配。该算法减少了圆锥角膜GP适配（KAKC设计）与健康眼睛中标准GP（BIAS设计）镜片适配之间的差异。
