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氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描（FDG PET/CT）在一例表现为巨大颅外颅内肿块的罕见多发性骨髓瘤病例中的发现。

Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (FDG PET/CT) Findings in an Unusual Case of Multiple Myeloma Presenting with a Large Extra-Axial Intracranial Mass.

作者信息

Ayaz Sevin, Ayaz Ümit Yaşar

机构信息

Department of Nuclear Medicine, Mersin State Hospital, Mersin, Turkey.

Department of Radiology, Mersin Women's and Children's Hospital, Mersin, Turkey.

出版信息

Pol J Radiol. 2016 Dec 16;81:602-605. doi: 10.12659/PJR.899444. eCollection 2016.

DOI:10.12659/PJR.899444
PMID:28058074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5175789/
Abstract

BACKGROUND

We aimed to present unusual cranial FDG PET/CT findings of a 56-year-old female with multiple myeloma (MM).

CASE REPORT

Plain CT images revealed a lytic lesion in the right parietal bone, filled with an oval-shaped, large, extra-axial, extradural, intracranial mass which measured 75×75×40 mm and had smooth borders. The right parietal lobe was compressed by the mass. The maximum standardized uptake value (SUV) of the mass lesion was 8.94 on FDG PET/CT images. Multiple lytic lesions with an increased uptake were also detected in other calvarial bones, in several vertebras and in the proximal left femur. After seven months, a control FDG PET/CT following radiotherapy and chemotherapy revealed almost complete regression of the right parietal extra-axial mass lesion. The number, size and metabolism of lytic lesions in other bones also decreased.

CONCLUSIONS

FDG PET/CT was useful for an initial evaluation of MM lesions and was effective in monitoring the response of these lesions to therapy.

摘要

背景

我们旨在展示一名56岁多发性骨髓瘤（MM）女性患者不寻常的颅骨FDG PET/CT表现。

病例报告

平扫CT图像显示右侧顶骨有一个溶骨性病变，内有一个椭圆形、巨大、轴外、硬膜外、颅内肿块，大小为75×75×40 mm，边界光滑。右侧顶叶被肿块压迫。在FDG PET/CT图像上，肿块病变的最大标准化摄取值（SUV）为8.94。在其他颅骨、多个椎体和左股骨近端也检测到多个溶骨性病变且摄取增加。七个月后，放疗和化疗后的对照FDG PET/CT显示右侧顶骨轴外肿块病变几乎完全消退。其他骨骼中溶骨性病变的数量、大小和代谢也有所减少。

结论

FDG PET/CT对MM病变的初始评估有用，并且在监测这些病变对治疗的反应方面有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/f22ab5be5cf1/poljradiol-81-602-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/2473a9813a92/poljradiol-81-602-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/486b74eb5b89/poljradiol-81-602-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/faaa92a29aa2/poljradiol-81-602-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/8f5070f25852/poljradiol-81-602-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/f22ab5be5cf1/poljradiol-81-602-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/2473a9813a92/poljradiol-81-602-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/486b74eb5b89/poljradiol-81-602-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/faaa92a29aa2/poljradiol-81-602-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/8f5070f25852/poljradiol-81-602-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3df/5175789/f22ab5be5cf1/poljradiol-81-602-g005.jpg

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