Polat Nihat, Gunduz Abuzer
Department of Ophthalmology, Medical Faculty, Inönü University, Malatya, Turkey.
J Ophthalmol. 2016;2016:3437125. doi: 10.1155/2016/3437125. Epub 2016 Dec 12.
To obtain information about effect of cycloplegia on keratometry and biometry in keratoconus. 48 keratoconus (Group 1) and 52 healthy subjects (Group 2) were included in the study. We measured the flat meridian of the anterior corneal surface (K1), steep meridian of the anterior corneal surface (K2), lens thickness (LT), anterior chamber depth (ACD), and axial length (AL) using the Lenstar LS 900 before and after cycloplegia. The median K1 in Group 1 was 45.64 D before and 45.42 D after cycloplegia, and the difference was statistically significant ( < 0.05). The median K2 in Group 1 was 50.96 D before and 50.17 D after cycloplegia, and the difference was significant ( < 0.05). The median K1 and K2 in Group 2 were 42.84 and 44.49 D, respectively, before cycloplegia, and 42.84 and 44.56 D after cycloplegia, and the differences were not statistically significant (all > 0.05). There were significant differences in SE, LT, ACD, and RLP between before and after cycloplegia in either Group 1 (all < 0.05) or Group 2 (all < 0.05). There were not statistically significant differences in AL between before cycloplegia and after cycloplegia in either Group 1 ( = 0.533) or group 2 ( = 0.529). Flattened corneal curvature and increase in ACD following cycloplegia in keratoconus patients were detected.
为获取睫状肌麻痹对圆锥角膜角膜曲率测量及生物测量的影响的相关信息。本研究纳入了48例圆锥角膜患者（第1组）和52例健康受试者（第2组）。我们使用Lenstar LS 900在睫状肌麻痹前后测量了角膜前表面的扁平子午线（K1）、角膜前表面的陡峭子午线（K2）、晶状体厚度（LT）、前房深度（ACD）和眼轴长度（AL）。第1组中，睫状肌麻痹前K1的中位数为45.64D，睫状肌麻痹后为45.42D，差异具有统计学意义（<0.05）。第1组中，睫状肌麻痹前K2的中位数为50.96D，睫状肌麻痹后为50.17D，差异具有统计学意义（<0.05）。第2组中，睫状肌麻痹前K1和K2的中位数分别为42.84D和44.49D，睫状肌麻痹后分别为42.84D和44.56D，差异无统计学意义（均>0.05）。第1组（均<0.05）和第2组（均<0.05）在睫状肌麻痹前后的等效球镜度、LT、ACD和RLP方面均存在显著差异。第1组（=0.533）和第2组（=0.529）在睫状肌麻痹前后的AL方面均无统计学差异。检测到圆锥角膜患者在睫状肌麻痹后角膜曲率变平以及ACD增加。
