De Malet Ana, Ingerto Sheila, Gañán Israel
Microbiology Department, Hospital Comarcal Valdeorras, Avenida Conde de Fenosa, No. 50, CP 32300, O Barco, Ourense, Spain.
Pediatrics Department, Hospital Comarcal Valdeorras, Avenida Conde de Fenosa, No. 50, CP 32300, O Barco, Ourense, Spain.
Case Rep Infect Dis. 2016;2016:2145805. doi: 10.1155/2016/2145805. Epub 2016 Dec 12.
is a Gram-negative bacillus belonging to the Enterobacteria family and the nontyphi Salmonella (NTS), usually related to gastroenteritis. Main difference between NTS and is that the last one evolves to an invasive disease easier than NTS. These can progress to bacteremias in around 5% of cases and secondary focuses can appear occasionally, as in meningitis. An infection of the central nervous system is uncommon, considering its incidence in 0.6-8% of the cases; most of them are described in developing countries and mainly in childhood, especially neonates. Bacterial meningitis by NTS mostly affects immunosuppressed people in Europe. Prognosis is adverse, with a 50% mortality rate, mainly due to complications of infection: hydrocephalus, ventriculitis, abscesses, subdural empyema, or stroke. Choice antibiotic treatments are cefotaxime, ceftriaxone, or ceftazidime. The aim of this paper is to present a case of meningitis caused by diagnosed in a five-year-old girl living in a rural area of the province of Ourense (Spain), with favorable evolution and without neurological disorders.
是一种革兰氏阴性杆菌,属于肠杆菌科和非伤寒沙门氏菌(NTS),通常与肠胃炎有关。NTS与该菌的主要区别在于,该菌比NTS更容易发展为侵袭性疾病。在大约5%的病例中,这些情况会发展为菌血症,偶尔会出现继发性病灶,如脑膜炎。考虑到其在0.6 - 8%的病例中的发病率,中枢神经系统感染并不常见;大多数病例在发展中国家被描述,主要发生在儿童时期,尤其是新生儿。在欧洲,由NTS引起的细菌性脑膜炎主要影响免疫功能低下的人群。预后不良,死亡率为50%,主要是由于感染并发症:脑积水、脑室炎、脓肿、硬膜下积脓或中风。选择的抗生素治疗药物是头孢噻肟、头孢曲松或头孢他啶。本文的目的是介绍一例由该菌引起的脑膜炎病例,该病例发生在西班牙奥伦塞省农村地区的一名五岁女孩身上,病情发展良好且无神经障碍。