Misirli Handan Cemile, Yanar Havva Tugba, Erdogan Serife Nese, Akkilic Elvan Cevizci, Ozkan Duygu, Bayram Tamer, Araz Ozkan
Department of Neurology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.
Department of Neurology, Erzurum Horasan State Hospital, Erzurum, Turkey.
North Clin Istanb. 2015 Apr 23;2(1):7-12. doi: 10.14744/nci.2015.83007. eCollection 2015.
The study aimed to evaluate the frequency of left atrial dilatation in cases of first-ever acute ischemic stroke with or without atrial fibrillation in a cohort of patients hospitalized for ischemic stroke.
Files of 120 patients admitted to our hospital with the diagnosis of acute ischemic stroke were investigated. All patients had at least one brain imaging. Etiology of stroke was categorized according to Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification. Transthoracic and/or transoesophageal echocardiography was used to measure left atrium size. Optimal cut-off value of left atrial diameter was determined as 4 cm. SPSS 11.5 was used for statistical analyses.
In 40% of the patients, left atrial dilatation was detected. Nineteen patients with left atrial dilatation had atrial fibrillation, which was statistically significant (p<0.05). Ninety-four (30.8%) patients with no atrial fibrillation had left atrial dilatation. In the TOAST classification trial, as a statistically significant finding, left atrial dilatation was detected 68.9% of the patients with cardioembolic infarcts. The most frequently encountered risk factor in patients was hypertension.
Left atrial dilatation is an important marker for cerebrovascular diseases, and if accompanied by atrial fibrillation becomes even more significant.
本研究旨在评估因急性缺血性卒中住院的患者队列中,首次发生急性缺血性卒中且伴有或不伴有房颤的患者左心房扩张的频率。
对我院收治的120例诊断为急性缺血性卒中的患者病历进行调查。所有患者至少进行了一次脑部影像学检查。卒中病因根据急性卒中治疗中Org 10172试验(TOAST)分类进行归类。采用经胸和/或经食管超声心动图测量左心房大小。左心房直径的最佳截断值确定为4 cm。使用SPSS 11.5进行统计分析。
40%的患者检测到左心房扩张。19例左心房扩张患者伴有房颤,具有统计学意义(p<0.05)。94例(30.8%)无房颤患者存在左心房扩张。在TOAST分类试验中,作为一项具有统计学意义的发现,68.9%的心源性栓塞性梗死患者检测到左心房扩张。患者中最常见的危险因素是高血压。
左心房扩张是脑血管疾病的重要标志物,若伴有房颤则更为显著。