Xiao Guang-Qian, Unger Pamela D
1 Keck Medical Center of the University of Southern California, Los Angeles, CA, USA.
2 Lenox Hill Hospital-Northwell Health, New York, NY, USA.
Int J Surg Pathol. 2017 Jun;25(4):344-347. doi: 10.1177/1066896916685835. Epub 2017 Jan 6.
Signet ring cell prostatic intraepithelial neoplasia is a rare speculated variant of high-grade prostatic intraepithelial neoplasia (HGPIN). Here, we present a free-standing and isolated signet ring cell HGPIN that was not associated with invasive carcinoma on needle biopsy and demonstrated the existence of this type of HGPIN variant. The differentiation between HGPIN and intraductal carcinoma of prostate is also discussed.
印戒细胞前列腺上皮内瘤变是高级别前列腺上皮内瘤变（HGPIN）一种罕见的推测性变体。在此，我们展示了一例独立且孤立的印戒细胞HGPIN，其在穿刺活检时与浸润性癌无关，并证实了这种HGPIN变体的存在。同时也讨论了HGPIN与前列腺导管内癌之间的鉴别诊断。
