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多发性硬化症患者九孔插钉试验的可靠性、精确性及临床重要变化

Reliability, precision, and clinically important change of the Nine-Hole Peg Test in individuals with multiple sclerosis.

作者信息

Hervault Mario, Balto Julia M, Hubbard Elizabeth A, Motl Robert W

机构信息

Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

出版信息

Int J Rehabil Res. 2017 Mar;40(1):91-93. doi: 10.1097/MRR.0000000000000209.

DOI:10.1097/MRR.0000000000000209
PMID:28059944
Abstract

This study evaluated the reliability, precision, and clinically important change of the Nine-Hole Peg Test (9-HPT) over a 1-week period. Sixty-nine patients with multiple sclerosis completed the 9-HPT on two occasions 1 week apart. Test-retest reliability was based on intraclass correlation coefficient, and precision was based on standard error of measurement and coefficient of variation. Clinically important change was based on the minimal detectable change. Intraclass correlation coefficients exceed 0.90 for all 9-HPT metrics. Standard error of measurements for dominant (DH) and nondominant (NDH) hand time were 1.58 and 2.69 s, and 0.03 peg/s for both DH and nondominant NDH speed, respectively. Coefficient of variations for DH and NDH time were 4.3 and 3.8%, and 4.5 and 4.6% for DH and NDH speed. Minimal detectable changes for DH and NDH time were 19.4 and 29.1%, and 18.6 and 20.5% for DH and NDH speed. These data provide evidence on reliability, precision, and clinically important change of the 9-HPT over a 1-week period in multiple sclerosis for clinicians and researchers.

摘要

本研究评估了九孔插钉试验(9-HPT)在1周时间内的可靠性、精密度以及临床重要变化。69例多发性硬化患者在相隔1周的时间内分两次完成了9-HPT测试。重测信度基于组内相关系数,精密度基于测量标准误差和变异系数。临床重要变化基于最小可检测变化。所有9-HPT指标的组内相关系数均超过0.90。优势手(DH)和非优势手(NDH)完成时间的测量标准误差分别为1.58秒和2.69秒,DH和NDH速度的测量标准误差均为0.03钉/秒。DH和NDH时间的变异系数分别为4.3%和3.8%,DH和NDH速度的变异系数分别为4.5%和4.6%。DH和NDH时间的最小可检测变化分别为19.4%和29.1%,DH和NDH速度的最小可检测变化分别为18.6%和20.5%。这些数据为临床医生和研究人员提供了关于9-HPT在多发性硬化患者1周时间内的可靠性、精密度以及临床重要变化的证据。

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