Adran Daniel, Vaillancourt Louis, Harissi-Dagher Mona, Kruh Jonathan N, Syed Zeba A, Robinson Steven, Melki Samir
*Boston Eye Group, Boston, MA; †Boston University, Boston, MA; ‡Notre Dame Hospital, Montreal, QC, Canada; §Jamaica Hospital Medical Center, Jamaica, NY; and ¶Massachusetts Eye & Ear Infirmary, Boston, MA.
Cornea. 2017 Apr;36(4):406-410. doi: 10.1097/ICO.0000000000001114.
This study evaluates the correlation between corneal densitometry and epithelial ingrowth (EI) after laser in situ keratomileusis (LASIK).
Corneal densitometry of 3 patients who developed EI after LASIK was measured with the Oculus Pentacam. Corneal densitometry readings of each patient were obtained preoperatively and postoperatively after ingrowth was discovered. Densitometry was recorded at the central nest of opacity and at the leading edges of EI.
For all patients, the most severe stages of EI observed on slit-lamp photographs correlated with the highest densitometry readings, with peak densitometry ranging from 73.3 to 95.1. These values were much higher than preoperative densitometry readings, which ranged from 21.8 to 27.2. In 2 cases, the Pentacam densitometry map revealed progression of EI toward the visual axis that was only faintly detectable or not detectable at all on the corresponding slit-lamp photographs.
Corneal densitometry seems to be an objective measure of the severity and progression of EI after LASIK.
本研究评估准分子原位角膜磨镶术（LASIK）后角膜密度测量与上皮内生（EI）之间的相关性。
使用欧科路眼前节分析系统（Oculus Pentacam）测量3例LASIK术后发生EI患者的角膜密度。在发现内生后，获取每位患者术前和术后的角膜密度测量读数。在混浊中心窝和EI前缘记录密度测量值。
对于所有患者，裂隙灯照片上观察到的最严重EI阶段与最高密度测量读数相关，密度测量峰值范围为73.3至95.1。这些值远高于术前密度测量读数，术前读数范围为21.8至27.2。在2例患者中，眼前节分析系统角膜密度测量图显示EI向视轴进展，而在相应的裂隙灯照片上仅能微弱检测到或根本检测不到。
角膜密度测量似乎是LASIK术后EI严重程度和进展的客观指标。
