Munikoty Vinay, Bhatia Anmol, Bansal Deepak, Das Ashim, Khandelwal Niranjan
Departments of *Pediatrics †Gastroenterology ‡Histopathology §Radiodiagnosis and Imaging, PGIMER, Chandigarh, India.
J Pediatr Hematol Oncol. 2017 May;39(4):309-310. doi: 10.1097/MPH.0000000000000726.
Malignancy is the most common etiology of acquired fistulae between the tracheobronchial tree and esophagus. The majority are due to either primary bronchial or esophageal carcinoma, and are typically observed in adult population. The occurrence of tracheoesophageal fistula (TEF) in patients with Hodgkin lymphoma is a rare phenomenon.
We report a rare case of Hodgkin lymphoma with TEF in a 10-year-old girl at presentation. She also developed pulmonary tuberculosis later during the follow up. She was fed through a nasogastric tube to avoid aspiration through the fistulous tract. She did well with chemotherapy and anti-tubercular therapy.
Our case suggests TEF in Hodgkin lymphoma at the time of diagnosis is a rare complication in pediatric age group. Lymphoma-related TEF require far less active intervention, as against esophageal or bronchial malignancy related TEF.
恶性肿瘤是气管支气管树与食管之间后天性瘘管最常见的病因。大多数是由于原发性支气管癌或食管癌,通常在成年人群中观察到。霍奇金淋巴瘤患者发生气管食管瘘(TEF)是一种罕见现象。
我们报告一例10岁女童初诊时患有霍奇金淋巴瘤并伴有TEF的罕见病例。在后续随访中她还患上了肺结核。通过鼻胃管喂养以避免经瘘管误吸。她接受化疗和抗结核治疗后情况良好。
我们的病例表明,诊断时霍奇金淋巴瘤并发TEF在儿童年龄组中是一种罕见的并发症。与淋巴瘤相关的TEF相比食管或支气管恶性肿瘤相关的TEF,所需的积极干预要少得多。