Perry R R, Rosenberg R K, Pass H I
Thoracic Oncology Section, National Cancer Institute, Bethesda, Md. 20892.
Surgery. 1989 Jun;105(6):770-7.
Tracheoesophageal fistula (TEF) occurs only rarely in the patient with lymphoma. Two cases are presented to illustrate the challenges in managing TEF in this patient population. Most of the 38 previously reported cases have occurred in patients who have undergone radiation therapy, although several patients have had TEF as an initial manifestation of lymphoma. TEF is usually, but not universally, associated with the presence of active lymphoma. The surgical approach should be individualized, based on the patient's overall condition, the site and size of the fistula, and sites of disease. Often a conservative surgical approach is warranted with the expectation that many of these fistulas will close after radiation therapy or chemotherapy. Patients with lymphoma-related TEF have a better prognosis than do those with TEF caused by carcinoma of the lung or esophagus.
气管食管瘘（TEF）在淋巴瘤患者中极为罕见。现报告两例以说明在这一患者群体中处理TEF所面临的挑战。先前报告的38例病例中，大多数发生在接受过放射治疗的患者中，尽管有几例患者以TEF作为淋巴瘤的初始表现。TEF通常（但并非普遍）与活动性淋巴瘤的存在相关。手术方法应根据患者的整体状况、瘘管的部位和大小以及疾病部位进行个体化。通常采用保守的手术方法，期望许多此类瘘管在放射治疗或化疗后会闭合。与淋巴瘤相关的TEF患者的预后比由肺癌或食管癌引起的TEF患者要好。
