DNA 折纸驱动的光刻技术，可在金表面实现亚 10nm 分辨率的图案化。

DNA-Origami-Driven Lithography for Patterning on Gold Surfaces with Sub-10 nm Resolution.

机构信息

Institute for Advanced Chemistry of Catalonia (IQAC), Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Spanish National Research Council (CSIC), Barcelona, 08034, Spain.

MIND-IN2UB, Department of Engineering: Electronics, University of Barcelona, Barcelona, 08028, Spain.

出版信息

Adv Mater. 2017 Mar;29(11). doi: 10.1002/adma.201603233. Epub 2017 Jan 6.

DOI:10.1002/adma.201603233

PMID:28060403

Abstract

Sub-10 nm lithography of DNA patterns is achieved using the DNA-origami stamping method. This new strategy utilizes DNA origami to bind a preprogrammed DNA ink pattern composed of thiol-modified oligonucleotides on gold surfaces. Upon denaturation of the DNA origami, the DNA ink pattern is exposed. The pattern can then be developed by hybridization with complementary strands carrying gold nanoparticles.

摘要

采用 DNA 折纸印章方法实现了亚 10nm 的 DNA 图案光刻。该新策略利用 DNA 折纸将由巯基修饰的寡核苷酸组成的预编程的 DNA 墨水图案结合到金表面上。在 DNA 折纸变性后，暴露 DNA 墨水图案。然后可以通过与携带金纳米粒子的互补链杂交来开发该图案。