近期发病的神经性厌食症年轻女性及康复者嗅觉敏感性增强。
Heightened Olfactory Sensitivity in Young Females with Recent-Onset Anorexia Nervosa and Recovered Individuals.
作者信息
Bentz Mette, Guldberg Johanne, Vangkilde Signe, Pedersen Tine, Plessen Kerstin Jessica, Jepsen Jens Richardt Moellegaard
机构信息
Child and Adolescent Mental Health Centre, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark.
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
出版信息
PLoS One. 2017 Jan 6;12(1):e0169183. doi: 10.1371/journal.pone.0169183. eCollection 2017.
INTRODUCTION
Olfaction may be related to food restriction and weight loss. However, reports regarding olfactory function in individuals with anorexia nervosa (AN) have been inconclusive.
OBJECTIVE
Characterize olfactory sensitivity and identification in female adolescents and young adults with first-episode AN and young females recovered from AN.
METHODS
We used the Sniffin' Sticks Odor Threshold Test and Odor Identification Test to assess 43 participants with first-episode AN, 27 recovered participants, and 39 control participants. Participants completed the Importance of Olfaction questionnaire, the Beck Youth Inventory and the Eating Disorder Inventory. We also conducted a psychiatric diagnostic interview and the Autism Diagnostic Observation Schedule with participants.
RESULTS
Both clinical groups showed heightened olfactory sensitivity. After excluding participants with depression, participants with first-episode AN identified more odors than recovered participants.
CONCLUSION
Heightened olfactory sensitivity in AN may be independent of clinical status, whereas only individuals with current AN and without depression show more accurate odor identification.
引言
嗅觉可能与食物限制和体重减轻有关。然而，关于神经性厌食症（AN）患者嗅觉功能的报告尚无定论。
目的
描述首次发作的AN女性青少年和年轻成年人以及从AN中康复的年轻女性的嗅觉敏感性和识别能力。
方法
我们使用嗅棒气味阈值测试和气味识别测试来评估43名首次发作的AN参与者、27名康复参与者和39名对照参与者。参与者完成了嗅觉重要性问卷、贝克青少年量表和饮食失调量表。我们还对参与者进行了精神科诊断访谈和自闭症诊断观察量表评估。
结果
两个临床组均表现出嗅觉敏感性增强。在排除抑郁症患者后，首次发作的AN患者比康复患者识别出更多气味。
结论
AN患者嗅觉敏感性增强可能与临床状态无关，而只有当前患有AN且无抑郁症的个体表现出更准确的气味识别能力。
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