Pattern Recognition Lab, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Med Phys. 2017 Sep;44(9):e125-e137. doi: 10.1002/mp.12094. Epub 2017 Feb 10.
Cone beam computed tomography (CBCT) suffers from a large amount of scatter, resulting in severe scatter artifacts in the reconstructions. Recently, a new scatter correction approach, called improved primary modulator scatter estimation (iPMSE), was introduced. That approach utilizes a primary modulator that is inserted between the X-ray source and the object. This modulation enables estimation of the scatter in the projection domain by optimizing an objective function with respect to the scatter estimate. Up to now the approach has not been implemented on a clinical angiography C-arm CT system.
In our work, the iPMSE method is transferred to a clinical C-arm CBCT. Additional processing steps are added in order to compensate for the C-arm scanner motion and the automatic X-ray tube current modulation. These challenges were overcome by establishing a reference modulator database and a block-matching algorithm. Experiments with phantom and experimental in vivo data were performed to evaluate the method.
We show that scatter correction using primary modulation is possible on a clinical C-arm CBCT. Scatter artifacts in the reconstructions are reduced with the newly extended method. Compared to a scan with a narrow collimation, our approach showed superior results with an improvement of the contrast and the contrast-to-noise ratio for the phantom experiments. In vivo data are evaluated by comparing the results with a scan with a narrow collimation and with a constant scatter correction approach.
Scatter correction using primary modulation is possible on a clinical CBCT by compensating for the scanner motion and the tube current modulation. Scatter artifacts could be reduced in the reconstructions of phantom scans and in experimental in vivo data.
锥形束计算机断层扫描(CBCT)会产生大量散射,导致重建图像中出现严重的散射伪影。最近,一种新的散射校正方法,称为改进的初级调制散射估计(iPMSE),已经被提出。该方法利用插入在 X 射线源和物体之间的初级调制器。通过优化目标函数相对于散射估计来估计投影域中的散射,从而实现这种调制。到目前为止,该方法尚未在临床血管造影 C 臂 CT 系统上实现。
在我们的工作中,将 iPMSE 方法转移到临床 C 臂 CBCT 上。为了补偿 C 臂扫描仪的运动和自动 X 射线管电流调制,添加了额外的处理步骤。通过建立参考调制器数据库和块匹配算法,克服了这些挑战。使用体模和实验体内数据进行了实验来评估该方法。
我们表明,在临床 C 臂 CBCT 上使用初级调制进行散射校正成为可能。通过新扩展的方法,重建中的散射伪影得以减少。与窄准直扫描相比,我们的方法在体模实验中表现出更好的结果,对比度和对比度噪声比都得到了提高。通过与窄准直扫描和恒定散射校正方法的结果进行比较,对体内数据进行了评估。
通过补偿扫描仪运动和管电流调制,在临床 CBCT 上可以使用初级调制进行散射校正。在体模扫描和实验体内数据的重建中,可以减少散射伪影。