外周注射组胺对大鼠脊髓中精氨酸加压素和催产素水平的急性影响。
Acute effects of peripheral histamine administration on arginine-8-vasopressin and oxytocin levels in rat spinal cord.
作者信息
Jójárt I, Vecsernyés M, Jójárt J, Laczi F, Szabó G, Kovács G L, Janáky T, László F A, Telegdy G
机构信息
First Department of Medicine, Albert Szent-Györgyi University Medical School, Szeged, Hungary.
出版信息
Endocrinol Exp. 1989 Sep;23(3):229-33.
The effects of a single injection of 20 mg/kg histamine on the immunoreactive arginine-8-vasopressin (AVP) and oxytocin (OXT) levels in the rat spinal cord were studied after peripheral (intraperitoneal) administration. Histamine induced a 60% elevation in the AVP content of the spinal cord, whereas the spinal level of OXT decreased by 36%. The findings suggest that peripheral histamine differentially affects the AVP and OXT levels in the spinal cord.
在大鼠经外周（腹腔内）给药后，研究了单次注射20mg/kg组胺对大鼠脊髓中免疫反应性精氨酸8 - 血管加压素（AVP）和催产素（OXT）水平的影响。组胺使脊髓中AVP含量升高60%，而脊髓中OXT水平下降36%。这些发现表明外周组胺对脊髓中AVP和OXT水平有不同的影响。
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