Vañó-Galván S, Camacho F
Servicio de Dermatología, Unidad de Tricología, Hospital Universitario Ramón y Cajal, IRYCIS, Universidad de Alcalá, Madrid, España.
Hospital Virgen Macarena, Sevilla, España.
Actas Dermosifiliogr. 2017 Apr;108(3):221-228. doi: 10.1016/j.ad.2016.11.010. Epub 2017 Jan 3.
The treatment of hair loss is an important part of clinical dermatology given the prevalence of the problem and great impact on patients' quality of life. Many new treatments have been introduced in recent years. This review summarizes the main ones in 4 groups: a) For androgenetic alopecia, we discuss new excipients for oral minoxidil, dutasteride, and finasteride as well as new forms of topical application; prostaglandin agonists and antagonists; low-level laser therapy; and regenerative medicine with Wnt signaling activators and stem cell therapy. b) For alopecia areata, Janus kinase inhibitors are reviewed. c) For frontal fibrosing alopecia, we discuss the use of antiandrogens and, for some patients, pioglitazone. d) Finally, we mention new robotic devices for hair transplant procedures and techniques for optimal follicular unit extraction.
鉴于脱发问题的普遍性及其对患者生活质量的重大影响,脱发治疗是临床皮肤科的重要组成部分。近年来已引入了许多新的治疗方法。本综述总结了4组主要治疗方法:a)对于雄激素性脱发,我们讨论了口服米诺地尔、度他雄胺和非那雄胺的新辅料以及新的局部应用形式;前列腺素激动剂和拮抗剂;低能量激光疗法;以及使用Wnt信号激活剂的再生医学和干细胞疗法。b)对于斑秃,综述了Janus激酶抑制剂。c)对于额部纤维性脱发,我们讨论了抗雄激素药物的使用,以及对一些患者使用吡格列酮。d)最后,我们提到了用于毛发移植手术的新型机器人设备以及优化毛囊单位提取的技术。