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2017年西班牙皮肤科医生治疗雄激素性脱发的处方习惯:一项横断面研究

Prescribing Habits for Androgenic Alopecia Among Dermatologists in Spain in 2017: A Cross-Sectional Study.

作者信息

Pindado-Ortega C, Saceda-Corralo D, Buendía-Castaño D, Fernández-González P, Moreno-Arrones Ó M, Fonda-Pascual P, Alegre-Sánchez A, Rodrigues-Barata A R, Vañó-Galván S

机构信息

Servicio de Dermatología, Hospital Ramón y Cajal, Madrid, España.

Servicio de Dermatología, Hospital Ramón y Cajal, Madrid, España.

出版信息

Actas Dermosifiliogr (Engl Ed). 2018 Jul-Aug;109(6):536-542. doi: 10.1016/j.ad.2018.02.006. Epub 2018 Apr 12.

Abstract

BACKGROUND

Topical minoxidil and oral finasteride are the only drugs approved for the treatment of androgenetic alopecia (AGA) in Spain. However, the management of this condition is highly variable because numerous treatments are used off-label. The main aim of this study was to describe the prescribing habits of dermatologists in Spain for male AGA (MAGA) and female AGA (FAGA).

MATERIAL AND METHODS

Descriptive cross-sectional study using online questionnaires completed by dermatologists working in Spain.

RESULTS

The responses of 241 dermatologists were analyzed. The most common treatments prescribed for MAGA were minoxidil (98%), oral finasteride (96%), nutricosmetics (44%), topical finasteride (37%), oral dutasteride (33%), platelet-rich plasma (14%), and low-level laser therapy (8%). For premenopausal FAGA, the most common treatments were topical minoxidil (98%), oral contraceptives (81%), nutricosmetics (72%), cyproterone acetate (58%), oral finasteride (39%), topical finasteride (39%), spironolactone (27%), platelet-rich plasma (20%), oral dutasteride (20%), oral flutamide (18%), and low-level laser therapy (7%). Finally, for postmenopausal FAGA, the most common treatments prescribed were topical minoxidil (98%), oral finasteride (84%), nutricosmetics (68%), topical finasteride (50%), oral dutasteride (35%), platelet-rich plasma (21%), spironolactone (16%), cyproterone acetate (16%), oral flutamide (9%), and low-level laser therapy (9%). A limitation of our study is that we did not analyze novel AGA treatments such as oral minoxidil and dutasteride mesotherapy.

CONCLUSIONS

The most common treatments prescribed for AGA by dermatologists in Spain are topical minoxidil, oral finasteride, and nutricosmetics for MAGA and postmenopausal FAGA and topical minoxidil, oral contraceptives, and nutricosmetics for premenopausal FAGA.

摘要

背景

外用米诺地尔和口服非那雄胺是西班牙仅有的被批准用于治疗雄激素性脱发(AGA)的药物。然而,由于众多治疗方法为超适应证用药,这种疾病的治疗方式差异很大。本研究的主要目的是描述西班牙皮肤科医生对男性AGA(MAGA)和女性AGA(FAGA)的处方习惯。

材料与方法

采用在线问卷对西班牙皮肤科医生进行描述性横断面研究。

结果

分析了241名皮肤科医生的回复。MAGA最常用的治疗方法是米诺地尔(98%)、口服非那雄胺(96%)、营养化妆品(44%)、外用非那雄胺(37%)、口服度他雄胺(33%)、富血小板血浆(14%)和低能量激光疗法(8%)。对于绝经前FAGA,最常用的治疗方法是外用米诺地尔(98%)、口服避孕药(81%)、营养化妆品(72%)、醋酸环丙孕酮(58%)、口服非那雄胺(39%)、外用非那雄胺(39%)、螺内酯(27%)、富血小板血浆(20%)、口服度他雄胺(20%)、口服氟他胺(18%)和低能量激光疗法(7%)。最后,对于绝经后FAGA,最常用的治疗方法是外用米诺地尔(98%)、口服非那雄胺(84%)、营养化妆品(68%)、外用非那雄胺(50%)、口服度他雄胺(35%)、富血小板血浆(21%)、螺内酯(16%)、醋酸环丙孕酮(16%)、口服氟他胺(9%)和低能量激光疗法(9%)。本研究的一个局限性是我们没有分析新型AGA治疗方法,如口服米诺地尔和度他雄胺中胚层疗法。

结论

西班牙皮肤科医生治疗AGA最常用的方法是,MAGA和绝经后FAGA使用外用米诺地尔、口服非那雄胺和营养化妆品,绝经前FAGA使用外用米诺地尔、口服避孕药和营养化妆品。

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