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[急性阑尾炎与登革热并存:一例报告]

[Coexistence of acute appendicitis and dengue fever: A case report].

作者信息

Osuna-Ramos Juan Fidel, Silva-Gracia Carlos, Maya-Vacio Gerardo Joel, Romero-Utrilla Alejandra, Ríos-Burgueño Efrén Rafael, Velarde-Félix Jesús Salvador

机构信息

Facultad de Medicina, Universidad Autónoma de Sinaloa, Culiacán, Sinaloa, México.

Servicio de Cirugía General, Hospital General de Culiacán Bernardo J. Gástelum, Culiacán, Sinaloa, México.

出版信息

Cir Cir. 2017 Dec;85 Suppl 1:44-48. doi: 10.1016/j.circir.2016.11.009. Epub 2017 Jan 3.

Abstract

BACKGROUND

Dengue is the most important human viral disease transmitted by mosquitoes. It can be asymptomatic or it can present in any of its 3clinical forms: Dengue fever, dengue haemorrhagic fever and dengue shock syndrome. However, some atypical manifestations have been reported in surgical emergencies caused by acute appendicitis in patients with dengue fever.

CLINICAL CASE

We report the case of an 18-year-old Mexican male who presented to the emergency department of the General Hospital of Culiacan, Sinaloa, with symptoms of dengue fever, accompanied by crampy abdominal pain with positive Rovsing and Dunphy signs. Dengue infection was confirmed by a positive NS1 antigen test performed by enzyme-linked immunosorbent assay. An abdominal ultrasound revealed an appendicular process; as the abdominal pain in the right side kept increasing, an open appendectomy was performed. Abundant inflammatory liquid was observed during the surgery, and the pathology laboratory reported an oedematous appendix with fibrinopurulent plaques, which agreed with acute ulcerative appendicitis. The patient was discharged fully recovered without complications during the follow-up period.

CONCLUSIONS

Acute abdominal pain can be caused in some cases by dengue infection. This can be confusing, which can lead to unnecessary surgical interventions, creating additional morbidities and costs for the patient. This unusual and coincident acute appendicitis with dengue highlights the importance of performing careful clinical studies for appropriate decision making, especially in dengue endemic regions during an outbreak of this disease.

摘要

背景

登革热是由蚊子传播的最重要的人类病毒性疾病。它可以无症状,也可以表现为三种临床形式中的任何一种:登革热、登革出血热和登革休克综合征。然而,有报道称登革热患者急性阑尾炎引起的外科急症存在一些非典型表现。

临床病例

我们报告一例18岁墨西哥男性病例,该患者因登革热症状前往锡那罗亚州库利亚坎总医院急诊科就诊,伴有痉挛性腹痛,罗夫辛征和邓菲征阳性。通过酶联免疫吸附测定法检测NS1抗原呈阳性,确诊为登革热感染。腹部超声显示阑尾病变;由于右侧腹痛持续加重,遂行开腹阑尾切除术。手术中观察到大量炎性液体,病理实验室报告阑尾水肿,伴有纤维脓性斑块,符合急性溃疡性阑尾炎。患者出院时已完全康复,随访期间无并发症。

结论

在某些情况下,登革热感染可导致急性腹痛。这可能会造成混淆,导致不必要的手术干预,给患者带来额外的发病率和费用。这种登革热合并急性阑尾炎的不寻常情况凸显了进行仔细的临床研究以做出适当决策的重要性,特别是在登革热流行地区该病暴发期间。

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