McFarlane M E C, Plummer J M, Leake P A, Powell L, Chand V, Chung S, Tulloch K
Department of Surgery, Radiology, Anaesthetics and Intensive Care, University of the West Indies, Mona, Jamaica.
Int J Surg Case Rep. 2013;4(11):1032-4. doi: 10.1016/j.ijscr.2013.08.017. Epub 2013 Sep 8.
Dengue fever is an acute viral disease, which usually presents as a mild febrile illness. Patients with severe disease present with dengue haemorrhagic fever or dengue toxic shock syndrome. Rarely, it presents with abdominal symptoms mimicking acute appendicitis. We present a case of a male patient presenting with right iliac fossa pain and suspected acute appendicitis that was later diagnosed with dengue fever following a negative appendicectomy.
A 13-year old male patient presented with fever, localized right-sided abdominal pain and vomiting. Abdominal ultrasound was not helpful and appendicectomy was performed due to worsening abdominal signs and an elevated temperature. A normal appendix with enlarged mesenteric nodes was found at surgery. Complete blood count showed thrombocytopenia with leucopenia. Dengue fever was now suspected and confirmed by IgM enzyme-linked immunosorbent assay against dengue virus.
This unusual presentation of dengue fever mimicking acute appendicitis should be suspected during viral outbreaks and in patients with atypical symptoms and cytopenias on blood evaluation in order to prevent unnecessary surgery.
This case highlights the occurrence of abdominal symptoms and complications that may accompany dengue fever. Early recognition of dengue fever mimicking acute appendicitis will avoid non-therapeutic operation and the diagnosis may be aided by blood investigations indicating a leucopenia, which is uncommon in patients with suppurative acute appendicitis.
登革热是一种急性病毒性疾病,通常表现为轻度发热性疾病。重症患者会出现登革出血热或登革中毒性休克综合征。极少数情况下,它会表现出类似急性阑尾炎的腹部症状。我们报告一例男性患者,以右下腹疼痛就诊,疑似急性阑尾炎,在阑尾切除术后结果为阴性,随后被诊断为登革热。
一名13岁男性患者出现发热、右侧腹部局限性疼痛和呕吐。腹部超声检查无帮助,由于腹部体征恶化和体温升高,进行了阑尾切除术。手术中发现阑尾正常,但肠系膜淋巴结肿大。全血细胞计数显示血小板减少伴白细胞减少。此时怀疑为登革热,并通过针对登革病毒的IgM酶联免疫吸附试验得以确诊。
在病毒爆发期间以及血液检查出现非典型症状和血细胞减少的患者中,应怀疑这种模仿急性阑尾炎的登革热异常表现,以避免不必要的手术。
该病例突出了登革热可能伴随的腹部症状和并发症。早期识别模仿急性阑尾炎的登革热将避免进行无治疗意义的手术,血液检查显示白细胞减少有助于诊断,而这在化脓性急性阑尾炎患者中并不常见。