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走向数字化:电子健康技术在医院实践中临床及组织影响的叙述性概述

Going digital: a narrative overview of the clinical and organisational impacts of eHealth technologies in hospital practice.

作者信息

Keasberry Justin, Scott Ian A, Sullivan Clair, Staib Andrew, Ashby Richard

机构信息

Princess Alexandra Hospital, 199 Ipswich Road, Brisbane, Qld 4102, Australia. Email: ;

Metro South Hospital and Health Service, Garden City Park, 2404 Logan Road, Brisbane, Qld 4113, Australia. Email.

出版信息

Aust Health Rev. 2017 Dec;41(6):646-664. doi: 10.1071/AH16233.

Abstract

Objective The aim of the present study was to determine the effects of hospital-based eHealth technologies on quality, safety and efficiency of care and clinical outcomes. Methods Systematic reviews and reviews of systematic reviews of eHealth technologies published in PubMed/Medline/Cochrane Library between January 2010 and October 2015 were evaluated. Reviews of implementation issues, non-hospital settings or remote care or patient-focused technologies were excluded from analysis. Methodological quality was assessed using a validated appraisal tool. Outcome measures were benefits and harms relating to electronic medical records (EMRs), computerised physician order entry (CPOE), electronic prescribing (ePrescribing) and computerised decision support systems (CDSS). Results are presented as a narrative overview given marked study heterogeneity. Results Nineteen systematic reviews and two reviews of systematic reviews were included from 1197 abstracts, nine rated as high quality. For EMR functions, there was moderate-quality evidence of reduced hospitalisations and length of stay and low-quality evidence of improved organisational efficiency, greater accuracy of information and reduced documentation and process turnaround times. For CPOE functions, there was moderate-quality evidence of reductions in turnaround times and resource utilisation. For ePrescribing, there was moderate-quality evidence of substantially fewer medications errors and adverse drug events, greater guideline adherence, improved disease control and decreased dispensing turnaround times. For CDSS, there was moderate-quality evidence of increased use of preventive care and drug interaction reminders and alerts, increased use of diagnostic aids, more appropriate test ordering with fewer tests per patient, greater guideline adherence, improved processes of care and less disease morbidity. There was conflicting evidence regarding effects on in-patient mortality and overall costs. Reported harms were alert fatigue, increased technology interaction time, creation of disruptive workarounds and new prescribing errors. Conclusion eHealth technologies in hospital settings appear to improve efficiency and appropriateness of care, prescribing safety and disease control. Effects on mortality, readmissions, total costs and patient and provider experience remain uncertain. What is known about the topic? Healthcare systems internationally are undertaking large-scale digitisation programs with hospitals being a major focus. Although predictive analyses suggest that eHealth technologies have the potential to markedly transform health care delivery, contemporary peer-reviewed research evidence detailing their benefits and harms is limited. What does this paper add? This narrative overview of 19 systematic reviews and two reviews of systematic reviews published over the past 5 years provides a summary of cumulative evidence of clinical and organisational effects of contemporary eHealth technologies in hospital practice. EMRs have the potential to increase accuracy and completeness of clinical information, reduce documentation time and enhance information transfer and organisational efficiency. CPOE appears to improve laboratory turnaround times and decrease resource utilisation. ePrescribing significantly reduces medication errors and adverse drug events. CDSS, especially those used at the point of care and integrated into workflows, attract the strongest evidence for substantially increasing clinician adherence to guidelines, appropriateness of disease and treatment monitoring and optimal medication use. Evidence of effects of eHealth technologies on discrete clinical outcomes, such as morbid events, mortality and readmissions, is currently limited and conflicting. What are the implications for practitioners? eHealth technologies confer benefits in improving quality and safety of care with little evidence of major hazards. Whether EMRs and CPOE can affect clinical outcomes or overall costs in the absence of auxiliary support systems, such as ePrescribing and CDSS, remains unclear. eHealth technologies are evolving rapidly and the evidence base used to inform clinician and managerial decisions to invest in these technologies must be updated continually. More rigorous field research using appropriate evaluation methods is needed to better define real-world benefits and harms. Customisation of eHealth applications to the context of patient-centred care and management of highly complex patients with multimorbidity will be an ongoing challenge.

摘要

目的 本研究旨在确定基于医院的电子健康技术对医疗质量、安全性和效率以及临床结局的影响。方法 对2010年1月至2015年10月期间发表在PubMed/Medline/考克兰图书馆的电子健康技术的系统评价和系统评价的综述进行评估。排除关于实施问题、非医院环境或远程护理或以患者为中心的技术的综述。使用经过验证的评估工具评估方法学质量。结局指标为与电子病历(EMR)、计算机化医师医嘱录入(CPOE)、电子处方(ePrescribing)和计算机化决策支持系统(CDSS)相关的益处和危害。鉴于研究存在显著异质性,结果以叙述性综述的形式呈现。结果 从1197篇摘要中纳入了19篇系统评价和2篇系统评价的综述,9篇被评为高质量。对于EMR功能,有中等质量的证据表明住院率和住院时间减少,低质量的证据表明组织效率提高、信息准确性提高以及文档和流程周转时间减少。对于CPOE功能,有中等质量的证据表明周转时间和资源利用减少。对于电子处方,有中等质量的证据表明用药错误和药物不良事件大幅减少、指南依从性提高、疾病控制改善以及配药周转时间缩短。对于CDSS,有中等质量的证据表明预防性护理和药物相互作用提醒及警报的使用增加、诊断辅助工具的使用增加、每位患者的检查更合理且检查次数减少、指南依从性提高、护理流程改善以及疾病发病率降低。关于对住院死亡率和总体成本的影响存在相互矛盾的证据。报告的危害包括警报疲劳、技术交互时间增加、产生干扰性的变通方法和新的处方错误。结论 医院环境中的电子健康技术似乎可提高护理的效率和适当性、处方安全性及疾病控制。对死亡率、再入院率、总成本以及患者和提供者体验的影响仍不确定。关于该主题已知的内容有哪些?国际医疗保健系统正在开展大规模数字化项目,医院是主要重点。尽管预测性分析表明电子健康技术有可能显著改变医疗服务的提供方式,但详细阐述其益处和危害的当代同行评审研究证据有限。本文补充了哪些内容?这篇对过去5年发表的19篇系统评价和2篇系统评价的综述的叙述性综述,总结了当代电子健康技术在医院实践中的临床和组织影响的累积证据。EMR有可能提高临床信息的准确性和完整性,减少文档时间,增强信息传递和组织效率。CPOE似乎可改善实验室周转时间并降低资源利用。电子处方显著减少用药错误和药物不良事件。CDSS,尤其是那些在护理点使用并整合到工作流程中的CDSS,有最有力的证据表明可大幅提高临床医生对指南的依从性、疾病和治疗监测的适当性以及最佳用药。电子健康技术对离散临床结局(如不良事件、死亡率和再入院率)影响的证据目前有限且相互矛盾。对从业者有哪些启示?电子健康技术在提高护理质量和安全性方面具有益处,几乎没有重大危害的证据。在没有诸如电子处方和CDSS等辅助支持系统的情况下,EMR和CPOE是否能影响临床结局或总体成本仍不清楚。电子健康技术发展迅速,用于为临床医生和管理人员投资这些技术的决策提供信息的证据基础必须不断更新。需要使用适当评估方法进行更严格的实地研究,以更好地界定实际的益处和危害。将电子健康应用定制到以患者为中心的护理背景以及管理患有多种疾病的高度复杂患者将是一项持续的挑战。

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