Eur Heart J Cardiovasc Imaging. 2017 May 1;18(5):531-535. doi: 10.1093/ehjci/jew276.
To determine the prevalence of baffle leaks in adults after atrial switch operations for transposition of the great arteries, as these may predispose to paradoxical embolic events, particularly in patients with transvenous pacemaker or defibrillator leads.
We routinely perform contrast echocardiography with agitated saline in all patients after atrial switch operations. For this study, we analysed patients who had saline contrast echocardiography between 2010 and 2012. The presence of baffle leaks and the severity of right-to-left shunting were assessed. We compared baseline characteristics and oxygen saturation at rest and during exercise between patients with and without baffle leaks. A total of 65 patients (56 Senning and 9 Mustard repair) without previously known baffle leaks were included (mean age 32 ± 8 years, 77% males). Right-to-left shunting was identified in 42 patients (65%) and occurred without provocation manoeuvres in 88%. There were no differences in baseline characteristics, echocardiographic findings, or exercise capacity between patients with and without baffle leaks, except for lower oxygen saturation at peak exercise in those with baffle leaks (29% had oxygen saturations below 90% at peak exercise compared to none without baffle leaks, P = 0.011). Four patients with baffle leaks had previous implantation of transvenous pacemaker leads; one of them had suffered a stroke. Two other patients with baffle leaks had a history of potential embolic stroke.
Because of the high prevalence of baffle leaks in adults after atrial switch operations, we propose routine screening with agitated saline contrast, particularly prior to implantation of transvenous pacemaker or defibrillator leads.
确定成人房间隔转换术后房室旁路漏的发生率,因为这些旁路漏可能导致反常栓塞事件,尤其是在伴有经静脉起搏器或除颤器导线的患者中。
我们常规对所有房间隔转换术后患者进行含搅动盐水的超声心动图造影。为此研究,我们分析了 2010 年至 2012 年间接受盐水超声心动图造影的患者。评估房室旁路漏的存在和右向左分流的严重程度。我们比较了有和无房室旁路漏患者的基线特征和静息及运动时的氧饱和度。共纳入 65 例(56 例 Senning 手术和 9 例 Mustard 修复)无已知房室旁路漏的患者(平均年龄 32±8 岁,77%为男性)。42 例(65%)患者存在右向左分流,88%在无诱发操作时发生。有和无房室旁路漏患者的基线特征、超声心动图表现或运动能力无差异,除了有旁路漏的患者在运动峰值时的氧饱和度较低(42 例中有 29%的患者在运动峰值时的氧饱和度低于 90%,而无旁路漏的患者无一例低于 90%,P=0.011)。4 例有房室旁路漏的患者曾植入经静脉起搏器导线;其中 1 例曾发生过卒中。另外 2 例有房室旁路漏的患者有潜在的栓塞性卒中病史。
由于成人房间隔转换术后房室旁路漏的发生率较高,我们建议常规进行含搅动盐水的超声心动图造影筛查,尤其是在植入经静脉起搏器或除颤器导线之前。