Makhdoom Asadullah, Rahopoto Muhammad Qasim, Awan Shazia, Tahir Syed Muhammad, Memon Shazia, Siddiqui Khaleeque Ahmed
Bone Mass Density Assessment Unit, Liaquat University of Medical & Health Sciences, Jamshoro, Sindh Pakistan.
Department of Medicine, Liaquat University of Medical & Health Sciences, Jamshoro, Sindh Pakistan.
J Pak Med Assoc. 2017 Jan;67(1):15-19.
To observe the level of bone mineral density by Dual Energy X-ray Absorptiometry in rheumatoid arthritis patients.
The observational study was conducted at Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan, from January 2011 to December 2014. Bone mineral density was measured from the femoral neck, ward's triangle and lumbar spine, in patients 25-55 years of age, who were diagnosed with rheumatoid arthritis. All the cases were assessed for bone mineral density from appendicular as well as axial skeleton. Data was collected through a designed proforma and analysis was performed using SPSS 21.
Of the 229 rheumatoid arthritis patients, 33(14.4%) were males. Five (15.1%) males had normal bone density, 14(42.4%) had osteopenia and 14(42.4%) had osteoporosis. Of the 196(85.5%) females, 45(29.9%) had normal bone density, 72 (37.7%) had osteopenia and 79(40.30%) had osteoporosis. Of the 123(53.7%) patients aged 30-50 years, 38(30.9%) had normal bone density, 59(48.0%) had osteopenia, and 26(21.1%) had osteoporosis. Of the 106(46.3%) patients over 50 years, 12(11.3%) had normal bone density, 27 (25.5%) had osteopenia and 67(63.2%) had osteoporosis.
Osteoporosis and osteopenia were most common among rheumatoid arthritis patients. Assessment of bone mineral density by Dual Energy X-ray Absorptiometry can lead to quick relief in the clinical symptoms with timely therapy.
采用双能X线吸收法观察类风湿关节炎患者的骨密度水平。
2011年1月至2014年12月在巴基斯坦詹姆肖罗的利亚卡特医学与健康科学大学开展了一项观察性研究。对年龄在25 - 55岁、被诊断为类风湿关节炎的患者，测量其股骨颈、沃德三角区和腰椎的骨密度。所有病例均评估了四肢骨骼和中轴骨骼的骨密度。通过设计好的表格收集数据，并使用SPSS 21进行分析。
在229例类风湿关节炎患者中，男性33例（14.4%）。5例（15.1%）男性骨密度正常，14例（42.4%）骨量减少，14例（42.4%）骨质疏松。在196例（85.5%）女性中，45例（29.9%）骨密度正常，72例（37.7%）骨量减少，79例（40.30%）骨质疏松。在123例（53.7%）年龄在30 - 50岁的患者中，38例（30.9%）骨密度正常，59例（48.0%）骨量减少，26例（21.1%）骨质疏松。在106例（46.3%）年龄超过50岁的患者中，12例（11.3%）骨密度正常，27例（25.5%）骨量减少，67例（63.2%）骨质疏松。
骨质疏松和骨量减少在类风湿关节炎患者中最为常见。采用双能X线吸收法评估骨密度，及时治疗可使临床症状迅速缓解。
