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体外受精程序中的卵子捐赠：一种实现周期同步和胚胎移植时机的替代方法。

Egg donation in an in vitro fertilization program: an alternative approach to cycle synchronization and timing of embryo transfer.

作者信息

Ben-Nun I, Ghetler Y, Gruber A, Jaffe R, Fejgin M

机构信息

Department of Obstetrics and Gynecology A, Meir General Hospital, KfarSaba, Israel.

出版信息

Fertil Steril. 1989 Oct;52(4):683-7. doi: 10.1016/s0015-0282(16)60988-3.

DOI:10.1016/s0015-0282(16)60988-3
PMID:2806610
Abstract

A new flexible protocol for the induction of recipient endometrial cycles is presented. For stimulation of endometrial growth, a fixed dose of conjugated estrogens, 3.75 mg/d was employed. The duration of the proliferative phase varied from 9 to 14 days, thus being adjusted to match the length of the follicular phase of the donor. Embryo transfer was performed on the fifth day of progesterone administration. Four term pregnancies resulted from 12 treatment cycles. In the conception cycles, the hormonal support was continued until the luteal placental shift occurred, regardless of gestational age.

摘要

本文提出了一种诱导受体子宫内膜周期的新的灵活方案。为刺激子宫内膜生长，采用了固定剂量的结合雌激素，即3.75毫克/天。增殖期持续时间为9至14天，从而根据供体卵泡期的长度进行调整。在给予孕酮的第5天进行胚胎移植。12个治疗周期中有4例足月妊娠。在受孕周期中，无论孕周如何，激素支持都持续到黄体 - 胎盘转换发生。

相似文献

1
Egg donation in an in vitro fertilization program: an alternative approach to cycle synchronization and timing of embryo transfer.体外受精程序中的卵子捐赠：一种实现周期同步和胚胎移植时机的替代方法。
Fertil Steril. 1989 Oct;52(4):683-7. doi: 10.1016/s0015-0282(16)60988-3.
2
An insight into early reproductive processes through the in vivo model of ovum donation.通过卵子捐赠的体内模型深入了解早期生殖过程。
J Clin Endocrinol Metab. 1991 Feb;72(2):408-14. doi: 10.1210/jcem-72-2-408.
3
Endometrial preparation: effect of estrogen dose and administration route on reproductive outcomes in oocyte donation cycles with fresh embryo transfer.子宫内膜准备：雌激素剂量和给药途径对新鲜胚胎移植卵母细胞捐赠周期生殖结局的影响。
Hum Reprod. 2016 Aug;31(8):1755-64. doi: 10.1093/humrep/dew099. Epub 2016 May 1.
4
The effect of clomid induced superovulation on human follicular and luteal function for extracorporeal fertilization and embryo transfer.克罗米酚诱导超排卵对体外受精和胚胎移植中人类卵泡及黄体功能的影响。
Clin Reprod Fertil. 1983 Jun;2(2):129-42.
5
The window of embryo transfer and the efficiency of human conception in vitro.胚胎移植窗口与人类体外受精效率
Fertil Steril. 1991 Jan;55(1):114-8. doi: 10.1016/s0015-0282(16)54069-2.
6
The establishment of an ovum donation program using a simple fixed-dose estrogen-progesterone replacement regimen.使用简单的固定剂量雌激素 - 孕激素替代方案建立卵子捐赠计划。
J In Vitro Fert Embryo Transf. 1990 Oct;7(5):244-8. doi: 10.1007/BF01129527.
7
The role of preparatory cycles in ovum donation recipients: a retrospective study.准备周期在卵子捐赠受者中的作用：一项回顾性研究。
J Assist Reprod Genet. 2004 Nov;21(11):377-9. doi: 10.1007/s10815-004-7524-9.
8
Ovum donation by sisters in ovarian failure: simplified priming and early withdrawal of exogenous support.卵巢功能衰竭姐妹间的卵子捐赠：简化预处理及早期撤除外部支持
J In Vitro Fert Embryo Transf. 1989 Aug;6(4):228-31. doi: 10.1007/BF01132870.
9
A flexible protocol for the induction of recipient endometrial cycles in an oocyte donation programme.在卵母细胞捐赠计划中诱导受体子宫内膜周期的灵活方案。
Hum Reprod. 1996 May;11(5):1063-6. doi: 10.1093/oxfordjournals.humrep.a019297.
10
PROST for ovum donation.用于卵子捐赠的PROST。
Lancet. 1987 May 23;1(8543):1209-10. doi: 10.1016/s0140-6736(87)92185-4.

引用本文的文献

1
Controlled ovarian hyperstimulation adversely affects implantation following in vitro fertilization-embryo transfer.控制性卵巢过度刺激对体外受精-胚胎移植后的着床有不利影响。
J Assist Reprod Genet. 1999 Sep;16(8):416-20. doi: 10.1023/a:1020565408018.
2
The significance of an early (premature) rise of plasma progesterone in in vitro fertilization cycles induced by a "long protocol" of gonadotropin releasing hormone analogue and human menopausal gonadotropins.在促性腺激素释放激素类似物和人绝经期促性腺激素的“长方案”诱导的体外受精周期中，血浆孕酮过早升高的意义。
J Assist Reprod Genet. 1996 Mar;13(3):207-11. doi: 10.1007/BF02065937.
3
Ovum donation--an overview.
卵子捐赠——概述
J Assist Reprod Genet. 1993 Feb;10(2):105-11. doi: 10.1007/BF01207729.
4
The effect of a prolonged artificial follicular phase on endometrial development in an oocyte donation program.在卵母细胞捐赠计划中延长人工卵泡期对子宫内膜发育的影响。
J In Vitro Fert Embryo Transf. 1991 Apr;8(2):84-8. doi: 10.1007/BF01138660.
5
Comparison of pregnancy rates following in vitro fertilization-embryo transfer between the donors and the recipients in a donor oocyte program.供卵计划中供体与受体体外受精-胚胎移植后的妊娠率比较。
J Assist Reprod Genet. 1992 Jun;9(3):248-50. doi: 10.1007/BF01203822.
6
Artificial endometrial preparation for oocyte donation: the effect of estrogen stimulation on clinical outcome.供卵体外受精人工子宫内膜准备：雌激素刺激对临床结局的影响。
J Assist Reprod Genet. 1992 Jun;9(3):222-7. doi: 10.1007/BF01203817.
7
Lack of correlation between hormonal blood levels and endometrial maturation in agonadal women with repeat implantation failure following embryo transfer from donated eggs.
J Assist Reprod Genet. 1992 Apr;9(2):102-5. doi: 10.1007/BF01203747.