Nakajima T, Tomizawa M, Hasegawa S, Ohnishi M, Tokiwa N
J Oral Surg. 1978 Nov;36(11):873-7.
In addition to replacement therapy with antihemophilic factor (AHF), its concentrated solution was used topically after dental extractions in hemophilic patients. The results, compared with that of the control extraction sites in the same patients, indicated that the topical application of AHF is effective in producing rapid and tight clot formation and in reducing postoperative oozing of blood.
