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延髓腹侧结构对体循环动脉血压及骨骼肌血管阻力和容量的影响

[The effect of the ventral structures of the medulla oblongata on systemic arterial pressure and on the resistance and capacitance of the skeletal muscle vessels].

作者信息

Kul'chitskiĭ V A, Tkachenko B I

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1989 Jun;75(6):786-92.

PMID:2806645
Abstract

Following the isolation of ventral portions of the medulla oblongata from the dorsal ones and from the upper parts of the c. n. s. in cats, no changes were found in the initial level of systemic blood pressure, in perfusion pressure or in venous outflow in the m. gastrocnemius, vessels. Electrical stimulation of ventral portions of the lateral paragigantocellular nucleus under these conditions increased the systemic AP, regional vascular resistance and decreased the capacitance of the n. gastrocnemius' vessels, whereas after bilateral electrical coagulation of the nucleus the stimulation led to a stable and obvious decrease in the systemic AP and perfusion pressure in the muscle vessels. No changes of the regional vascular capacitance were noted. The significance of ventral structures of medulla oblongata in maintaining of initial AP level, formation of tonic neurogenic messages to arterial vessels of m. gastrocnemius and in actualization of the reflex neurogenic effects upon arterial and venous vessels of skeletal muscles, is discussed.

摘要

在猫身上将延髓腹侧部分与背侧部分以及中枢神经系统上部隔离后,未发现全身血压初始水平、灌注压或腓肠肌血管静脉流出量有变化。在这些条件下,电刺激外侧旁巨细胞腹侧核会使全身动脉压升高、局部血管阻力增加,并降低腓肠肌血管的容量,而在该核进行双侧电凝后,刺激会导致全身动脉压和肌肉血管灌注压稳定且明显下降。未观察到局部血管容量的变化。本文讨论了延髓腹侧结构在维持初始动脉压水平、向腓肠肌动脉血管形成紧张性神经源性信息以及实现对骨骼肌动脉和静脉血管的反射性神经源性效应方面的意义。

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Fiziol Zh SSSR Im I M Sechenova. 1989 Jun;75(6):786-92.
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