Targeting tumorigenicity of breast cancer stem-like cells using combination epigenetic therapy: something old and something new.
作者信息
Huang Yi, Davidson Nancy E
机构信息
University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA;; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA;; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
出版信息
J Thorac Dis. 2016 Nov;8(11):2971-2974. doi: 10.21037/jtd.2016.11.18.
Abstract
摘要
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本文引用的文献
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Epigenetics: Separate paths for epigenomes and genomes in cancer evolution?表观遗传学：癌症演变中表观基因组和基因组的不同路径？
Nat Rev Genet. 2016 Jul 15;17(8):438. doi: 10.1038/nrg.2016.89.
2
Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth.DNA甲基转移酶（DNMT）和组蛋白去乙酰化酶（HDAC）的联合抑制可阻断癌症干细胞样细胞的致瘤性并减弱乳腺肿瘤生长。
Cancer Res. 2016 Jun 1;76(11):3224-35. doi: 10.1158/0008-5472.CAN-15-2249. Epub 2016 Apr 5.
3
Inhibition of histone deacetylases in cancer therapy: lessons from leukaemia.组蛋白去乙酰化酶抑制在癌症治疗中的应用：白血病的启示
Br J Cancer. 2016 Mar 15;114(6):605-11. doi: 10.1038/bjc.2016.36. Epub 2016 Feb 23.
4
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders.组蛋白去乙酰化酶及其抑制剂在癌症、神经疾病和免疫紊乱中的作用。
Nat Rev Drug Discov. 2014 Sep;13(9):673-91. doi: 10.1038/nrd4360. Epub 2014 Aug 18.
5
Brief reports: A distinct DNA methylation signature defines breast cancer stem cells and predicts cancer outcome.短篇报道：独特的 DNA 甲基化特征定义了乳腺癌干细胞，并预测了癌症结局。
Stem Cells. 2014 Nov;32(11):3031-6. doi: 10.1002/stem.1792.
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Epigenetic reprogramming in breast cancer: from new targets to new therapies.乳腺癌中的表观遗传重编程：从新靶点到新疗法。
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DNA methylation profiling in the clinic: applications and challenges.临床 DNA 甲基化分析：应用与挑战。
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