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III期非小细胞肺癌中剂量递增放疗是否能提高总生存期?

Did dose escalated radiotherapy in stage III non-small cell lung cancer improve overall survival?

作者信息

Wang Wei-Wei, Wang Shao-Jia, Zhou Zhi-Rui

机构信息

Department of Chest Surgery, The Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming 650031, China;; Department of Oncology, Kunming Medical University, Kunming 650031, China.

Department of Oncology, Kunming Medical University, Kunming 650031, China;; Department of Gynecological Oncology, The Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province), Kunming 650031, China.

出版信息

J Thorac Dis. 2016 Nov;8(11):3338-3342. doi: 10.21037/jtd.2016.11.13.

Abstract

Radiotherapy has been applied in the treatment for lung cancer patients for many years, especially those with advanced stage disease who cannot be treated with surgery. However, if these advanced stage patients should be treated with standard dosage therapy (60 Gy) or high dosage therapy (>60 Gy) remains a hot debated point. Literature related to this topic would be reviewed here. We believe standard dosage therapy should be strongly recommended, and high dosage therapy might benefit patients with high risk factors patients.

摘要

放射疗法已应用于肺癌患者的治疗多年,尤其是那些患有晚期疾病且无法进行手术治疗的患者。然而,这些晚期患者应该接受标准剂量治疗(60 Gy)还是高剂量治疗(>60 Gy)仍是一个备受争议的热点问题。本文将对与此主题相关的文献进行综述。我们认为应强烈推荐标准剂量治疗,而高剂量治疗可能使具有高危因素的患者受益。

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Cancer statistics in China, 2015.《中国癌症统计数据 2015》
CA Cancer J Clin. 2016 Mar-Apr;66(2):115-32. doi: 10.3322/caac.21338. Epub 2016 Jan 25.

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