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关于控制微流体通道中感应电流体动力学驱动的流动行为

On controlling the flow behavior driven by induction electrohydrodynamics in microfluidic channels.

作者信息

Li Yanbo, Ren Yukun, Liu Weiyu, Chen Xiaoming, Tao Ye, Jiang Hongyuan

机构信息

School of Electronics and Control Engineering, Chang'an University, Xi'an, Shaanxi, P. R. China.

School of Mechatronics Engineering, Harbin Institute of Technology, Harbin, Heilongjiang, P. R. China.

出版信息

Electrophoresis. 2017 Apr;38(7):983-995. doi: 10.1002/elps.201600500. Epub 2017 Feb 9.

DOI:10.1002/elps.201600500
PMID:28067427
Abstract

In this study, we develop a nondimensional physical model to demonstrate fluid flow at the micrometer dimension driven by traveling-wave induction electrohydrodynamics (EHD) through direct numerical simulation. In order to realize an enhancement in the pump flow rate as well as a flexible adjustment of anisotropy of flow behavior generated by induction EHD in microchannels, while not adding the risk of causing dielectric breakdown of working solution and material for insulation, a pair of synchronized traveling-wave voltage signals are imposed on double-sided electrode arrays that are mounted on the top and bottom insulating substrate, respectively. Accordingly, we present a model evidence, that not only the pump performance is improved evidently, but a variety of flow profiles, including the symmetrical and parabolic curve, plug-like shape and even biased flow behavior of quite high anisotropy are produced by the device design of "mix-type", "superimposition-type" and "adjustable-type" proposed herein as well, with the resulting controllable fluid motion being able to greatly facilitate an on-demand transportation mode of on-chip bio-microfluidic samples. Besides, automatic conversion in the direction of pump flow is achievable by switching on and off a second voltage wave. Our results provide utilitarian guidelines for constructing flexible electrokinetic framework useful in controllable transportation of particle and fluid samples in modern microfluidic systems.

摘要

在本研究中,我们通过直接数值模拟建立了一个无量纲物理模型,以展示行波感应电流体动力学(EHD)驱动的微米级流体流动。为了在不增加工作溶液和绝缘材料发生介电击穿风险的情况下,提高泵的流速并灵活调整微通道中感应EHD产生的流动行为各向异性,在分别安装于顶部和底部绝缘基板上的双面电极阵列上施加一对同步行波电压信号。据此,我们给出了一个模型证据,即不仅泵的性能得到了显著改善,而且本文提出的“混合型”“叠加型”和“可调型”器件设计还能产生各种流动剖面,包括对称抛物线曲线、塞状形状,甚至是具有相当高各向异性的偏置流动行为,由此产生的可控流体运动能够极大地促进片上生物微流体样品的按需运输模式。此外,通过开启和关闭第二个电压波,可以实现泵流方向的自动转换。我们的结果为构建灵活的电动框架提供了实用指导,该框架有助于现代微流体系统中颗粒和流体样品的可控运输。

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