利用生物动力学能量的自供电植入式药物输送系统。
A Self-Powered Implantable Drug-Delivery System Using Biokinetic Energy.
机构信息
Nanyang Environment and Water Research Institute, Nanyang Technological University, 1 Cleantech Loop, CleanTech One #06-08, Singapore, 637141, Singapore.
School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798, Singapore.
出版信息
Adv Mater. 2017 Mar;29(11). doi: 10.1002/adma.201605668. Epub 2017 Jan 9.
The first triboelectric-nanogenerator (TENG)-based self-powered implantable drug-delivery system is presented. Pumping flow rates from 5.3 to 40 µL min under different rotating speeds of the TENG are realized. The implantable drug-delivery system can be powered with a TENG device rotated by human hand motion. Ex vivo trans-sclera drug delivery in porcine eyes is demonstrated by utilizing the biokinetic energies of human hands.
本文提出了首个基于摩擦纳米发电机（TENG）的自供能植入式药物输送系统。在 TENG 的不同旋转速度下，实现了 5.3 至 40 µL min 的泵送流速。该植入式药物输送系统可以由 TENG 设备驱动，该 TENG 设备由人手运动旋转。通过利用人手的生物动力学能量，在猪眼的巩膜外进行了药物输送。
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