Vangipuram Ramya, Vaidya Toral, Jandarov Roman, Alikhan Ali
Center for Clinical Studies, Webster, TX, USA.
Dermatology. 2016;232(6):692-695. doi: 10.1159/000453259. Epub 2017 Jan 10.
Hidradenitis suppurativa (HS) is a debilitating chronic disease that leads to inflammation and abscess formation in the involved skin, along with a malodorous discharge. Pain is a considerable aspect of HS and significantly impacts quality of life. In addition, HS is significantly associated with depression. A better understanding of contributing factors to depression and pain in patients with HS can identify opportunities to improve care for patients.
To identify factors that contribute to depression and chronic pain in patients with HS.
This is a retrospective chart review of 283 patients seen at dermatology clinics of an academic health center for HS from July 2012 to December 2015. The association between HS and depression and chronic pain was assessed in multivariate models using logistic regression analyses.
Patients with a greater number of areas of involvement were more likely to have both chronic pain and depression.
This is a single-center retrospective chart review with a limited sample size.
This study suggests that the extent of disease rather than severity plays a role in reducing the quality of life in HS patients.
化脓性汗腺炎（HS）是一种使人衰弱的慢性疾病，会导致受累皮肤出现炎症和脓肿形成，并伴有恶臭分泌物。疼痛是HS的一个重要方面，对生活质量有显著影响。此外，HS与抑郁症显著相关。更好地了解HS患者抑郁和疼痛的促成因素可以找到改善患者护理的机会。
确定导致HS患者抑郁和慢性疼痛的因素。
这是一项对2012年7月至2015年12月在一所学术健康中心皮肤科诊所就诊的283例HS患者的回顾性病历审查。使用逻辑回归分析在多变量模型中评估HS与抑郁和慢性疼痛之间的关联。
受累部位数量较多的患者更有可能同时患有慢性疼痛和抑郁症。
这是一项单中心回顾性病历审查，样本量有限。
本研究表明，疾病的范围而非严重程度在降低HS患者生活质量方面起作用。
