Gintsburg A L, Grizhebovskiĭ G M, Tokarskaia O N, Ryskov A P, Briukhanov A V, Shaginian I A, Ianishevskiĭ N V, Smirov G B
Genetika. 1989 Jul;25(7):1320-4.
Population of atoxigenic Eltor vibrios (vct-) isolated from open water has been shown to be heterogeneous by the genomic fingerprinting technique. Epidemically dangerous strains (vct+) containing the gene coding for cholera toxin have similar hybridization profile independent of time and place of their isolation. The clonal formation of vct+ strains and the absence of vct----vct+ transition of strains under natural conditions are discussed.
通过基因组指纹技术已表明,从开阔水域分离出的无毒力埃尔托弧菌(vct-)群体具有异质性。含有霍乱毒素编码基因的具有流行危险性的菌株(vct+),无论其分离的时间和地点如何,都具有相似的杂交图谱。文中讨论了vct+菌株的克隆形成以及在自然条件下菌株不存在vct----vct+转变的情况。