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顺铂对晚期宫颈癌放疗增敏作用的长期随访

Long-term follow-up of potentiation of radiotherapy by cis-platinum in advanced cervical cancer.

作者信息

Wong L C, Choo Y C, Choy D, Sham J S, Ma H K

机构信息

Department of Obstetrics and Gynaecology, University of Hong Kong.

出版信息

Gynecol Oncol. 1989 Nov;35(2):159-63. doi: 10.1016/0090-8258(89)90035-8.

DOI:10.1016/0090-8258(89)90035-8
PMID:2807006
Abstract

Between January 1982 and January 1983 all patients with advanced cervical cancer were randomized into three groups: radiotherapy only (group I), radiotherapy plus weekly cis-platinum (group II), and radiation plus twice-weekly cis-platinum (group III). Better initial central control was observed in group III patients. Long-term survival was similar in the three groups. Potentiation of radiotherapy with cis-platinum failed to show any significant improvement in long-term survival.

摘要

1982年1月至1983年1月期间,所有晚期宫颈癌患者被随机分为三组:单纯放疗组(第一组)、放疗加每周一次顺铂组(第二组)和放疗加每周两次顺铂组(第三组)。第三组患者的初始中心控制情况更好。三组的长期生存率相似。顺铂对放疗的增敏作用未能在长期生存方面显示出任何显著改善。

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