Henniger M, Rehart S
Sektion Orthopädische Rheumatologie, Klinik für Orthopädie und Unfallchirurgie, Agaplesion Markus Krankenhaus, Wilhelm-Epstein-Str. 4, 60431, Frankfurt/M, Deutschland.
Unfallchirurg. 2017 Mar;120(3):214-219. doi: 10.1007/s00113-016-0291-0.
Involvement of tendons and tendon sheaths is frequently found in the most common inflammatory systemic diseases, rheumatoid arthritis and spondyloarthritis. In rheumatoid arthritis tendon manifestations occur as tenosynovitis, with swelling and pain of the tendons mainly on the hands and feet. In spondyloarthritis the involvement of tendons presents as enthesitis with pain and swelling directly at the attachment points of tendons to the bony structures and more commonly in the lower extremities. Pathological alterations of tendons can be normally visualized by sonography and only sometimes with magnetic resonance imaging (MRI) or scintigraphy. Furthermore, it is important for diagnostics and effective therapy to detect all joints involved by means of clinical, sonographic and radiological examination as well as laboratory parameters of inflammation, antibody serology (e.g. anti-CCP antibodies) and HLA-B27. The histopathological alterations of tendinopathy in rheumatic diseases differ from degenerative/posttraumatic tendinopathy in their expression of the changes; however, a clear differentiation of the different rheumatic inflammatory systemic diseases is histopathologically not possible. Therapeutically, systemic medication is the most important part of treatment in rheumatic diseases. Local therapeutic measures can be employed in the treatment of tenosynovitis and enthesitis. In the case of failure or lack of efficacy of the medication and conservative therapy, tenosynovectomy is performed for persistent tenosynovitis and reconstructive surgical procedures are necessary for tendon ruptures.
在最常见的炎症性全身性疾病——类风湿关节炎和脊柱关节炎中,经常会发现肌腱和腱鞘受累。在类风湿关节炎中,肌腱表现为腱鞘炎,主要是手部和足部的肌腱肿胀和疼痛。在脊柱关节炎中,肌腱受累表现为附着点炎,在肌腱与骨结构的附着点处出现疼痛和肿胀,且更常见于下肢。肌腱的病理改变通常可通过超声检查看到,有时也可通过磁共振成像(MRI)或闪烁扫描法看到。此外,通过临床、超声和放射学检查以及炎症实验室参数、抗体血清学(如抗环瓜氨酸肽抗体)和HLA - B27来检测所有受累关节,对于诊断和有效治疗很重要。风湿性疾病中肌腱病的组织病理学改变在变化表现上与退行性/创伤后肌腱病不同;然而,在组织病理学上无法明确区分不同的风湿性炎症性全身性疾病。在治疗方面,全身用药是风湿性疾病治疗的最重要部分。局部治疗措施可用于腱鞘炎和附着点炎的治疗。如果药物治疗和保守治疗失败或无效,对于持续性腱鞘炎需进行腱鞘切除术,对于肌腱断裂则需要进行重建性外科手术。