Ishikawa Takashi, Kaise Hiroshi, Yamada Kimito, Hosonaga Mari, Chishima Takashi, Narui Kazutaka, Yamada Akimitsu, Sugae Sadatoshi, Ichikawa Yasushi, Ota Mitsuyoshi, Nozaki Miwako, Mikami Ryuji, Tokuuye Koichi
Department of Breast Oncology and Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku, Tokyo, 160-0023, Japan.
Department of Breast Surgery, Yokohama Rosai Hospital, 3211 Kozukuecho, Kohokuku, Yokohama, 222-0036, Japan.
Breast Cancer. 2017 Jul;24(4):496-501. doi: 10.1007/s12282-016-0749-5. Epub 2017 Jan 9.
My arguments regarding postmastectomy radiotherapy (PMRT) for this case are based on the following 4 reasons: (1) high rate of local recurrence in the no PMRT group in the Early Breast Cancer Trialists' Collaborative Group meta-analysis on which the present guideline is based, (2) stage migration by sentinel node biopsy, (3) possible adverse events of radiotherapy, and (4) problems on extrapolation of data from western countries.