Department of Chemistry, CICECO, University of Aveiro , Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.
J Am Chem Soc. 2017 Jan 25;139(3):1057-1060. doi: 10.1021/jacs.6b11925. Epub 2017 Jan 13.
Capsules with a liquefied core were fabricated via the assembly of polymeric droplets induced by superamphiphobic surfaces. These highly repellent substrates exhibit distinct features such as (i) an easy and precise control over the particle size and shape, (ii) a high encapsulation efficiency, (iii) mild processing conditions, and (iv) the possibility to include any object in either a water or oil-based liquid core, which are not found on the current available strategies. As proof of concept, a photo-cross-linkable derivative of chitosan was used to produce the polymeric shell while a wealth variety of template cores were tested using a reversible cross-linking mechanism, interfacial gelation process or ice. Owing to the widespread application of polymeric capsules, the developed strategy is poised to usher the development of the next generation of materials not only for biomedical purposes but also for cosmetics, agriculture and electronics.
通过超疏液表面诱导的聚合液滴组装，制备了具有液态核的胶囊。这些高斥水性的基底具有独特的特性，如（i）易于精确控制颗粒的大小和形状，（ii）高封装效率，（iii）温和的处理条件，以及（iv）可以将任何物体包裹在水基或油基的液体核中，这是目前现有策略所不具备的。作为概念验证，使用壳聚糖的光交联衍生物来制备聚合壳，同时使用可逆交联机制、界面凝胶化过程或冰来测试各种模板核。由于聚合物胶囊的广泛应用，所开发的策略有望引领下一代材料的发展，不仅在生物医学领域，而且在化妆品、农业和电子领域。
